Kinases


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Kinases

DESCRIPTION

Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins. The phosphate generally comes from adenosine triphosphate (ATP). Kinases and phosphatases, which remove phosphate groups, are involved in nearly all signal transduction processes, often with cascades of phosphorylation events.

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90 sg:ontologies/subjects/computational-chemistry
91 sg:ontologies/subjects/dna
92 sg:ontologies/subjects/drug-delivery
93 sg:ontologies/subjects/enzyme-mechanisms
94 sg:ontologies/subjects/enzymes
95 sg:ontologies/subjects/glycobiology
96 sg:ontologies/subjects/glycomics
97 sg:ontologies/subjects/ion-channels
98 sg:ontologies/subjects/kinases
99 sg:ontologies/subjects/lipidomics
100 sg:ontologies/subjects/lipids
101 sg:ontologies/subjects/mechanism-of-action
102 sg:ontologies/subjects/membranes
103 sg:ontologies/subjects/metabolic-pathways
104 sg:ontologies/subjects/metabolomics
105 sg:ontologies/subjects/metals
106 sg:ontologies/subjects/natural-products
107 sg:ontologies/subjects/networks-and-systems-biology
108 sg:ontologies/subjects/nucleic-acids
109 sg:ontologies/subjects/peptides
110 sg:ontologies/subjects/pharmacology
111 sg:ontologies/subjects/post-translational-modifications
112 sg:ontologies/subjects/proteases
113 sg:ontologies/subjects/protein-design
114 sg:ontologies/subjects/protein-folding
115 sg:ontologies/subjects/proteins
116 sg:ontologies/subjects/proteomics
117 sg:ontologies/subjects/rna
118 sg:ontologies/subjects/screening
119 sg:ontologies/subjects/small-molecules
120 sg:ontologies/subjects/synthetic-biology
121 sg:ontologies/subjects/target-identification
122 sg:ontologies/subjects/target-validation
123 sg:ontologies/subjects/transporters
124 skos:prefLabel Chemical biology
125 sg:ontologies/subjects/enzymes sgo:sdDataset onto_subjects
126 rdf:type npg:Subject
127 skos:Concept
128 rdfs:label Enzymes
129 skos:altLabel Biocatalysts
130 skos:broader sg:ontologies/subjects/biochemistry
131 sg:ontologies/subjects/chemical-biology
132 skos:definition Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological catalysts, enzymes work by lowering a reaction’s activation energy barrier, thereby increasing the rate of the reaction. They also improve the specificity of the reactions.
133 skos:inScheme sg:ontologies/subjects/
134 skos:narrower sg:ontologies/subjects/catalytic-dna
135 sg:ontologies/subjects/catalytic-rna
136 sg:ontologies/subjects/dna-repair-enzymes
137 sg:ontologies/subjects/dna-restriction-modification-enzymes
138 sg:ontologies/subjects/holoenzymes
139 sg:ontologies/subjects/hydrolases
140 sg:ontologies/subjects/immobilized-enzymes
141 sg:ontologies/subjects/isoenzymes
142 sg:ontologies/subjects/isomerases
143 sg:ontologies/subjects/kinases
144 sg:ontologies/subjects/ligases
145 sg:ontologies/subjects/multienzyme-complexes
146 sg:ontologies/subjects/oxidoreductases
147 sg:ontologies/subjects/penicillin-binding-proteins
148 sg:ontologies/subjects/proteases
149 sg:ontologies/subjects/recombinases
150 sg:ontologies/subjects/transferases
151 skos:prefLabel Enzymes
152 skos:Concept sgo:sdDataset for_codes
153 rdf:type rdfs:Class
154 rdfs:Resource
155 rdfs:subClassOf rdfs:Resource
156 skos:Concept
 




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