Immunology


Ontology type: npg:Subject  | skos:Concept     

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immunology", 
    "rdfs:label": "Immunology", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Allergies (Specialty)"
      }, 
      {
        "@language": "en", 
        "@value": "Allergy and Immunology"
      }, 
      {
        "@language": "en", 
        "@value": "Allergy (Specialty)"
      }, 
      {
        "@language": "en", 
        "@value": "Immunology and Allergy"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphatic-system"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/bone-marrow-transplantation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/translational-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/gene-regulation-in-immune-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/infection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/haematopoiesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/autoimmunity"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphocytes"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/applied-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/inflammation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immune-evasion"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chemokines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/transplant-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cytokines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/antigen-processing-and-presentation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/imaging-the-immune-system"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunotherapy"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/coagulation-system"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/antimicrobial-responses"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunogenetics"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/tumour-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/mucosal-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immune-cell-death"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/adaptive-immunity"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/plant-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphoid-tissues"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/osteoimmunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cell-death-and-immune-response"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/complement-cascade"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunological-disorders"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/signal-transduction"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/innate-immune-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/neuroimmunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/innate-immunity"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/infectious-diseases"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/lymphatic-system", 
    "rdfs:label": "Lymphatic system", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Lymphatic Systems"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "The lymphatic system is a network of lymphoid organs and lymphatic vessels. It transports lymph fluid and helps to clear toxins and other waste from the body\u2019s tissues. Lymphocytes use the lymphatic system to circulate throughout the body, but it can also facilitate the spread of cancer cells. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphatic-vessels"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphangiogenesis"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Lymphatic system"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/vaccines", 
    "rdfs:label": "Vaccines", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/applied-immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/microbiology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Vaccines are a clinical product that is composed of live or dead material from an infectious agent \u2013 bacterium, virus, fungus or parasite \u2013 that elicit protective immunity against the pathogen when administered. These substances are used to prevent the spread of infectious diseases."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cell-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/conjugate-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/dna-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/inactivated-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/rna-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/live-attenuated-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/peptide-vaccines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/adjuvants"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/protein-vaccines"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Vaccines"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/bone-marrow-transplantation", 
    "rdfs:label": "Bone marrow transplantation", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Bone Marrow Cell Transplantation"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Bone marrow transplantation is the transference of bone marrow from one human or animal to another for a variety of purposes. Bone marrow transplantation can be used to treat certain blood disorders such as leukemia or immunodeficiency, but can also have serious complications such as graft-versus-host disease."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Bone marrow transplantation"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/translational-immunology", 
    "rdfs:label": "Translational immunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Translational immunology is the process by which researchers use immunological discoveries to develop practical solutions for human problems. Examples include the development of vaccines against infectious diseases or the engineering of new types of drugs to treat inflammatory disorders."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Translational immunology"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/gene-regulation-in-immune-cells", 
    "rdfs:label": "Gene regulation in immune cells", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/mirna-in-immune-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/epigenetics-in-immune-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunogenetics"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Gene regulation in immune cells"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/infection", 
    "rdfs:label": "Infection", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/pathogenesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Infection is the invasion by and multiplication of 'foreign' microorganisms that can cause pathological conditions or diseases in the host organism."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Infection"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/haematopoiesis", 
    "rdfs:label": "Haematopoiesis", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Medullary Hematopoiesis"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/developmental-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Haematopoiesis refers to the commitment and differentiation processes that lead to the formation of all blood cells from haematopoietic stem cells. In adults, haematopoiesis occurs mainly in the bone marrow (medullary), but it can also occur in other tissues such as the liver, thymus and spleen (extramedullary)."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/erythropoiesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/leukopoiesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/thrombopoiesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphopoiesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/myelopoiesis"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Haematopoiesis"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/autoimmunity", 
    "rdfs:label": "Autoimmunity", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Autoimmunities"
      }, 
      {
        "@language": "en", 
        "@value": "Autoimmune Responses"
      }, 
      {
        "@language": "en", 
        "@value": "Autoimmune Response"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Autoimmunity is a process by which the immune system reacts against the body's own tissues. Chronic and/or excessive autoimmune responses can result in autoimmune diseases."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Autoimmunity"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/lymphocytes", 
    "rdfs:label": "Lymphocytes", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Lymphoid Cells"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Lymphocytes are white blood cells that have important immune functions.  The main populations of lymphocytes are B cells, T cells and natural killer (NK) cells. They are typically (although not exclusively) associated with adaptive immune responses. Populations of novel innate-like lymphocytes were first described in 2010.   "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/b-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nk-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/t-cells"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Lymphocytes"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/applied-immunology", 
    "rdfs:label": "Applied immunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biotechnology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Applied immunology provides services to support the development of biological therapeutics such as monoclonal antibodies, vaccines and diagnostics. Applied immunology is a subdiscipline of immunology."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/vaccines"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Applied immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/inflammation", 
    "rdfs:label": "Inflammation", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Inflammations"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/pathogenesis"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Inflammation is a biological response to harmful stimuli, such as pathogens, damaged cells or irradiation. It is a protective attempt by the organism to remove injurious stimuli and to initiate the healing process. It is characterized by pain, redness, heat, swelling and disturbance of function."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/inflammasome"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/acute-inflammation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chronic-inflammation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/sepsis"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Inflammation"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immune-evasion", 
    "rdfs:label": "Immune evasion", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Immune Evasions"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immune evasion is a strategy used by pathogenic organisms and tumours to evade a host's immune response to maximize their probability of being transmitted to a fresh host or to continue growing, respectively."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immune evasion"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/chemokines", 
    "rdfs:label": "Chemokines", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Chemotactic Cytokines"
      }, 
      {
        "@language": "en", 
        "@value": "Intercrines"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cytokines"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Chemokines are a class of cytokine protein that act as signalling molecules, regulating immune and inflammatory responses; for example, modulating cell migration properties and localization of target cells such as leucokytes. The biological functions of chemokines are typically mediated by signalling through G protein-coupled chemokine receptors."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Chemokines"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/transplant-immunology", 
    "rdfs:label": "Transplant immunology", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Transplantation Immunology"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Transplant immunology is the study of the immune response that occurs when an organ or tissue is moved (grafted) from one individual to another. A major problem following transplantation is that the immune system of the recipient sees the grafted tissue as \u2018foreign\u2019 and attacks and destroys it."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/allograft"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/autograft"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Transplant immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/cytokines", 
    "rdfs:label": "Cytokines", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biochemistry"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes that regulate immune responses, haematopoiesis and lymphocyte development. Cytokines include interleukins, chemokines and  other signalling molecules. Each cytokine acts through its own receptor on target cells, and these receptors include members of the immunoglobulin (Ig) superfamily and tumour necrosis factor (TNF). "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/osteopontin"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/tumour-necrosis-factors"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/hepatocyte-growth-factor"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/transforming-growth-factor-beta"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/monokines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/leukaemia-inhibitory-factor"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/oncostatin-m"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphokines"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/interferons"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/interleukins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/autocrine-motility-factor"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/haematopoietic-cell-growth-factors"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chemokines"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Cytokines"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/antigen-processing-and-presentation", 
    "rdfs:label": "Antigen processing and presentation", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Antigen Processings"
      }, 
      {
        "@language": "en", 
        "@value": "Antigen Presentations"
      }, 
      {
        "@language": "en", 
        "@value": "Antigen Presentation"
      }, 
      {
        "@language": "en", 
        "@value": "Antigen Processing"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Antigen processing and presentation is the process by which protein antigen is ingested by an antigen-presenting cell (APC), partially digested into peptide fragments and then displayed on the surface of the APC associated with an antigen-presenting molecule such as MHC class I or MHC class II, for recognition by certain lymphocytes such as T cells. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/antigen-presenting-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/mhc"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Antigen processing and presentation"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/imaging-the-immune-system", 
    "rdfs:label": "Imaging the immune system", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Imaging the immune system involves a set of methods and analytical tools that are used to visualize immune responses at the cellular level as they occur in their native environment in real time."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Imaging the immune system"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immunotherapy", 
    "rdfs:label": "Immunotherapy", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Immunotherapies"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/therapeutics"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immunotherapy is the treatment of disease by inducing, enhancing or suppressing an immune response. Activation immunotherapies induce or amplify an immune response and are used in vaccines and as cancer immunotherapies. Suppression immunotherapies reduce or suppress an immune response and are used to prevent graft rejection and treat autoimmunity and allergy. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunization"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunosuppression"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immunotherapy"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/coagulation-system", 
    "rdfs:label": "Coagulation system", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "The coagulation system is composed of cells, proteins and processes that mediate blood clotting. Damage to a blood vessel wall triggers the system, initiating interactions between platelets and blood coagulation factors. This leads to the formation of a fibrin-containing clot, which stops bleeding and initiates vessel repair. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Coagulation system"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/antimicrobial-responses", 
    "rdfs:label": "Antimicrobial responses", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Antimicrobial responses refer to any host process triggered by the exposure to a microorganism that results in a change in state, activity or viability of the microorganism \u2013 for example, movement, secretion, enzyme production or gene expression."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Antimicrobial responses"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immunogenetics", 
    "rdfs:label": "Immunogenetics", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Immunogenetic"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/gene-regulation-in-immune-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/genetics"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immunogenetics is the study of the genetic basis of the immune response. It includes the study of normal immunological pathways and the identification of genetic variations that result in immune defects, which may result in the identification of new therapeutic targets for immune diseases."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immunogenetics"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/tumour-immunology", 
    "rdfs:label": "Tumour immunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cancer"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Tumour immunology describes the interaction between cells of the immune system with tumour cells. Understanding these interactions is important for the development of new therapies for cancer treatment."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunosurveillance"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Tumour immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/mucosal-immunology", 
    "rdfs:label": "Mucosal immunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Mucosal immunology is the study of immune responses that occur at mucosal surfaces, such as the intestines, the urogenital tract and the lungs. These tissues are closely associated with the external environment and the mucosal immune system must provide protective immunity to pathogens but remain tolerant of non-harmful environmental substances.  "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Mucosal immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immune-cell-death", 
    "rdfs:label": "Immune cell death", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Cell Death"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immune cell death is the process by which an immune cell undergoes cell death. There are various types of cell death mediated by intracellular programmes or external factors including apoptosis, necrosis, pyroptosis and necroptosis."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immune cell death"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/adaptive-immunity", 
    "rdfs:label": "Adaptive immunity", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Acquired Immunity"
      }, 
      {
        "@language": "en", 
        "@value": "Adaptive Immune Response"
      }, 
      {
        "@language": "en", 
        "@value": "Adoptive Immunity"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunopathogenesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly specific to a given antigen and is highly adaptable."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/class-switch-recombination"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immune-tolerance"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/clonal-selection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/humoral-immunity"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cellular-immunity"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/somatic-hypermutation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/vdj-recombination"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Adaptive immunity"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/plant-immunology", 
    "rdfs:label": "Plant immunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Plant immunology is the study of how plants defend their tissues from infection. Plants do not have an adaptive immune system, but have evolved innate immune mechanisms (including the resistance proteins) to sense and respond to infections. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Plant immunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/lymphoid-tissues", 
    "rdfs:label": "Lymphoid tissues", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Lymphatic Tissues"
      }, 
      {
        "@language": "en", 
        "@value": "Lymphatic Tissue"
      }, 
      {
        "@language": "en", 
        "@value": "Lymphoid Tissue"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Lymphoid tissues are organized structures that support immune responses. The bone marrow and thymus are primary lymphoid tissues and the sites of lymphocyte development. The lymph nodes, spleen, tonsils and Peyer\u2019s patches are examples of secondary lymphoid tissue. Chronic inflammation can lead to the development of tertiary lymphoid tissue. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/tonsils"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/bone-marrow"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/spleen"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/thymus"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymph-node"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Lymphoid tissues"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/osteoimmunology", 
    "rdfs:label": "Osteoimmunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/rheumatology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Osteoimmunology is the study of how the immune and skeletal systems interact."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Osteoimmunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/cell-death-and-immune-response", 
    "rdfs:label": "Cell death and immune response", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Cell Death"
      }, 
      {
        "@language": "en", 
        "@value": "Immune response"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Cell death is a process by which a cell's vital capacity is terminated. During an immune response, cells of the immune system cause the death of cells that are infected with microorganisms or are otherwise abnormal and remove dead cell fragments from the body. Failure to remove dead cells can cause inflammatory disease."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Cell death and immune response"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/complement-cascade", 
    "rdfs:label": "Complement cascade", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Complement pathway"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "The complement cascade is a biochemical process in the blood that helps or 'complements' cells of the immune system to eliminate invading pathogens. When activated by one of three pathways, a cascade of serial cleavage events results in a marked amplification of the immune response and formation of the cell-killing membrane attack complex."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Complement cascade"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/immunological-disorders", 
    "rdfs:label": "Immunological disorders", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Immunological Disease"
      }, 
      {
        "@language": "en", 
        "@value": "Immune Disorders"
      }, 
      {
        "@language": "en", 
        "@value": "Immunological Diseases"
      }, 
      {
        "@language": "en", 
        "@value": "Immune Diseases"
      }, 
      {
        "@language": "en", 
        "@value": "Immune Disorder"
      }, 
      {
        "@language": "en", 
        "@value": "Immune System Disease"
      }, 
      {
        "@language": "en", 
        "@value": "Immunologic Diseases"
      }, 
      {
        "@language": "en", 
        "@value": "Immune Disease"
      }, 
      {
        "@language": "en", 
        "@value": "Immunologic Disease"
      }, 
      {
        "@language": "en", 
        "@value": "Diseases of Immune System"
      }, 
      {
        "@language": "en", 
        "@value": "Immune System Diseases"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/diseases"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Immunological disorders are diseases or conditions caused by a dysfunction of the immune system and include allergy, asthma, autoimmune diseases, autoinflammatory syndromes and immunological deficiency syndromes."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/graft-versus-host-disease"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/thrombocytopaenic-purpura"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunological-deficiency-syndromes"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunoproliferative-disorders"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/primary-immunodeficiency-disorders"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/inflammatory-diseases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lymphoproliferative-disorders"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/autoimmune-diseases"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Immunological disorders"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/signal-transduction", 
    "rdfs:label": "Signal transduction", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Receptor Mediated Signal Transduction"
      }, 
      {
        "@language": "en", 
        "@value": "Receptor-Mediated Signal Transductions"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Transduction Pathway"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Pathways"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Pathway"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Transduction System"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Transduction Systems"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Transductions"
      }, 
      {
        "@language": "en", 
        "@value": "Signal Transduction Pathways"
      }, 
      {
        "@language": "en", 
        "@value": "Receptor-Mediated Signal Transduction"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nf-kappab"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Signal transduction"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/innate-immune-cells", 
    "rdfs:label": "Innate immune cells", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and NK cells. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/monocytes-and-macrophages"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/dendritic-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/innate-lymphoid-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/granulocytes"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Innate immune cells"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/neuroimmunology", 
    "rdfs:label": "Neuroimmunology", 
    "sdDataset": "onto_subjects", 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/neuroscience"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Neuroimmunology is a field that studies the interaction of the immune and nervous systems."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Neuroimmunology"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/innate-immunity", 
    "rdfs:label": "Innate immunity", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Disease Resistance"
      }, 
      {
        "@language": "en", 
        "@value": "Innate Immune Responses"
      }, 
      {
        "@language": "en", 
        "@value": "Non-specific immunity"
      }, 
      {
        "@language": "en", 
        "@value": "Non-Specific Immunity"
      }, 
      {
        "@language": "en", 
        "@value": "Innate Immune Response"
      }, 
      {
        "@language": "en", 
        "@value": "Native Immunity"
      }, 
      {
        "@language": "en", 
        "@value": "Natural Resistance"
      }, 
      {
        "@language": "en", 
        "@value": "Natural Immunity"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunopathogenesis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Innate immunity is an immunological subsystem that comprises the cells and mechanisms that provide the first line of defence from infection in a non-specific manner. Innate immune responses are rapid and independent of antigen. Innate immune systems are found in all classes of plants and animals."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/pattern-recognition-receptors"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Innate immunity"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/infectious-diseases", 
    "rdfs:label": "Infectious diseases", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Communicable Disease"
      }, 
      {
        "@language": "en", 
        "@value": "Communicable Diseases"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/diseases"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Infectious diseases \u0096 also known as contagious diseases, transmissible diseases or communicable diseases \u0096 are caused by pathogenic microorganisms that infect a host organism and can be spread, directly or indirectly, from one organism to another. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/helicobacter-pylori"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/neonatal-sepsis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/tuberculosis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/listeria"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/hiv-infections"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/bacterial-infection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/hepatitis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/meningitis"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/viral-infection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/parasitic-infection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/fungal-infection"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/clostridium-difficile"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/malaria"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/influenza-virus"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Infectious diseases"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://www.w3.org/2004/02/skos/core#Concept", 
    "rdfs:subClassOf": [
      {
        "id": "http://www.w3.org/2004/02/skos/core#Concept"
      }, 
      {
        "id": "http://www.w3.org/2000/01/rdf-schema#Resource"
      }
    ], 
    "sdDataset": "for_codes", 
    "type": [
      "http://www.w3.org/2000/01/rdf-schema#Resource", 
      "http://www.w3.org/2000/01/rdf-schema#Class"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences", 
    "rdfs:label": "Biological sciences", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Biologic Sciences"
      }, 
      {
        "@language": "en", 
        "@value": "Biologic Science"
      }, 
      {
        "@language": "en", 
        "@value": "Life Sciences"
      }, 
      {
        "@language": "en", 
        "@value": "Biological Science Discipline"
      }, 
      {
        "@language": "en", 
        "@value": "Biological Science"
      }, 
      {
        "@language": "en", 
        "@value": "Life Science"
      }, 
      {
        "@language": "en", 
        "@value": "Biological Science Disciplines"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cell-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biotechnology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/computational-biology-and-bioinformatics"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/physiology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/zoology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/evolution"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biochemistry"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/developmental-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/plant-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/neuroscience"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cancer"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/drug-discovery"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/ecology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/microbiology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biophysics"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/genetics"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/molecular-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/stem-cells"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chemical-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/psychology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-techniques"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/immunology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/systems-biology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/structural-biology"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Biological sciences"
      }
    ], 
    "skos:topConceptOf": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "dcterms:description": [
      {
        "@language": "en", 
        "@value": "The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature."
      }
    ], 
    "dcterms:title": [
      {
        "@language": "en", 
        "@value": "Nature Subjects Taxonomy"
      }
    ], 
    "id": "http://scigraph.springernature.com/ontologies/subjects/", 
    "sdDataset": "onto_subjects", 
    "skos:hasTopConcept": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/physical-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/DEPRECATED"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/business-and-commerce"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/humanities"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/social-science"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/health-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/scientific-community-and-society"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/earth-and-environmental-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#ConceptScheme"
    ]
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/immunology'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/immunology'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/immunology'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/immunology'


 

This table displays all metadata directly associated to this object as RDF triples.

557 TRIPLES      10 PREDICATES      50 URIs      8 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/immunology sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Immunology
6 skos:altLabel Allergies (Specialty)
7 Allergy (Specialty)
8 Allergy and Immunology
9 Immunology and Allergy
10 skos:broader sg:ontologies/subjects/biological-sciences
11 skos:definition Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms.
12 skos:inScheme sg:ontologies/subjects/
13 skos:narrower sg:ontologies/subjects/adaptive-immunity
14 sg:ontologies/subjects/antigen-processing-and-presentation
15 sg:ontologies/subjects/antimicrobial-responses
16 sg:ontologies/subjects/applied-immunology
17 sg:ontologies/subjects/autoimmunity
18 sg:ontologies/subjects/bone-marrow-transplantation
19 sg:ontologies/subjects/cell-death-and-immune-response
20 sg:ontologies/subjects/chemokines
21 sg:ontologies/subjects/coagulation-system
22 sg:ontologies/subjects/complement-cascade
23 sg:ontologies/subjects/cytokines
24 sg:ontologies/subjects/gene-regulation-in-immune-cells
25 sg:ontologies/subjects/haematopoiesis
26 sg:ontologies/subjects/imaging-the-immune-system
27 sg:ontologies/subjects/immune-cell-death
28 sg:ontologies/subjects/immune-evasion
29 sg:ontologies/subjects/immunogenetics
30 sg:ontologies/subjects/immunological-disorders
31 sg:ontologies/subjects/immunotherapy
32 sg:ontologies/subjects/infection
33 sg:ontologies/subjects/infectious-diseases
34 sg:ontologies/subjects/inflammation
35 sg:ontologies/subjects/innate-immune-cells
36 sg:ontologies/subjects/innate-immunity
37 sg:ontologies/subjects/lymphatic-system
38 sg:ontologies/subjects/lymphocytes
39 sg:ontologies/subjects/lymphoid-tissues
40 sg:ontologies/subjects/mucosal-immunology
41 sg:ontologies/subjects/neuroimmunology
42 sg:ontologies/subjects/osteoimmunology
43 sg:ontologies/subjects/plant-immunology
44 sg:ontologies/subjects/signal-transduction
45 sg:ontologies/subjects/translational-immunology
46 sg:ontologies/subjects/transplant-immunology
47 sg:ontologies/subjects/tumour-immunology
48 sg:ontologies/subjects/vaccines
49 skos:prefLabel Immunology
50 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
51 dcterms:title Nature Subjects Taxonomy
52 sgo:sdDataset onto_subjects
53 rdf:type skos:ConceptScheme
54 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
55 sg:ontologies/subjects/biological-sciences
56 sg:ontologies/subjects/business-and-commerce
57 sg:ontologies/subjects/earth-and-environmental-sciences
58 sg:ontologies/subjects/health-sciences
59 sg:ontologies/subjects/humanities
60 sg:ontologies/subjects/physical-sciences
61 sg:ontologies/subjects/scientific-community-and-society
62 sg:ontologies/subjects/social-science
63 sg:ontologies/subjects/adaptive-immunity sgo:sdDataset onto_subjects
64 rdf:type npg:Subject
65 skos:Concept
66 rdfs:label Adaptive immunity
67 skos:altLabel Acquired Immunity
68 Adaptive Immune Response
69 Adoptive Immunity
70 skos:broader sg:ontologies/subjects/immunology
71 sg:ontologies/subjects/immunopathogenesis
72 skos:definition Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly specific to a given antigen and is highly adaptable.
73 skos:inScheme sg:ontologies/subjects/
74 skos:narrower sg:ontologies/subjects/cellular-immunity
75 sg:ontologies/subjects/class-switch-recombination
76 sg:ontologies/subjects/clonal-selection
77 sg:ontologies/subjects/humoral-immunity
78 sg:ontologies/subjects/immune-tolerance
79 sg:ontologies/subjects/somatic-hypermutation
80 sg:ontologies/subjects/vdj-recombination
81 skos:prefLabel Adaptive immunity
82 sg:ontologies/subjects/antigen-processing-and-presentation sgo:sdDataset onto_subjects
83 rdf:type npg:Subject
84 skos:Concept
85 rdfs:label Antigen processing and presentation
86 skos:altLabel Antigen Presentation
87 Antigen Presentations
88 Antigen Processing
89 Antigen Processings
90 skos:broader sg:ontologies/subjects/immunology
91 skos:definition Antigen processing and presentation is the process by which protein antigen is ingested by an antigen-presenting cell (APC), partially digested into peptide fragments and then displayed on the surface of the APC associated with an antigen-presenting molecule such as MHC class I or MHC class II, for recognition by certain lymphocytes such as T cells.
92 skos:inScheme sg:ontologies/subjects/
93 skos:narrower sg:ontologies/subjects/antigen-presenting-cells
94 sg:ontologies/subjects/mhc
95 skos:prefLabel Antigen processing and presentation
96 sg:ontologies/subjects/antimicrobial-responses sgo:sdDataset onto_subjects
97 rdf:type npg:Subject
98 skos:Concept
99 rdfs:label Antimicrobial responses
100 skos:broader sg:ontologies/subjects/immunology
101 skos:definition Antimicrobial responses refer to any host process triggered by the exposure to a microorganism that results in a change in state, activity or viability of the microorganism – for example, movement, secretion, enzyme production or gene expression.
102 skos:inScheme sg:ontologies/subjects/
103 skos:prefLabel Antimicrobial responses
104 sg:ontologies/subjects/applied-immunology sgo:sdDataset onto_subjects
105 rdf:type npg:Subject
106 skos:Concept
107 rdfs:label Applied immunology
108 skos:broader sg:ontologies/subjects/biotechnology
109 sg:ontologies/subjects/immunology
110 skos:definition Applied immunology provides services to support the development of biological therapeutics such as monoclonal antibodies, vaccines and diagnostics. Applied immunology is a subdiscipline of immunology.
111 skos:inScheme sg:ontologies/subjects/
112 skos:narrower sg:ontologies/subjects/vaccines
113 skos:prefLabel Applied immunology
114 sg:ontologies/subjects/autoimmunity sgo:sdDataset onto_subjects
115 rdf:type npg:Subject
116 skos:Concept
117 rdfs:label Autoimmunity
118 skos:altLabel Autoimmune Response
119 Autoimmune Responses
120 Autoimmunities
121 skos:broader sg:ontologies/subjects/immunology
122 skos:definition Autoimmunity is a process by which the immune system reacts against the body's own tissues. Chronic and/or excessive autoimmune responses can result in autoimmune diseases.
123 skos:inScheme sg:ontologies/subjects/
124 skos:prefLabel Autoimmunity
125 sg:ontologies/subjects/biological-sciences sgo:sdDataset onto_subjects
126 rdf:type npg:Subject
127 skos:Concept
128 rdfs:label Biological sciences
129 skos:altLabel Biologic Science
130 Biologic Sciences
131 Biological Science
132 Biological Science Discipline
133 Biological Science Disciplines
134 Life Science
135 Life Sciences
136 skos:definition Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
137 skos:inScheme sg:ontologies/subjects/
138 skos:narrower sg:ontologies/subjects/biochemistry
139 sg:ontologies/subjects/biological-techniques
140 sg:ontologies/subjects/biophysics
141 sg:ontologies/subjects/biotechnology
142 sg:ontologies/subjects/cancer
143 sg:ontologies/subjects/cell-biology
144 sg:ontologies/subjects/chemical-biology
145 sg:ontologies/subjects/computational-biology-and-bioinformatics
146 sg:ontologies/subjects/developmental-biology
147 sg:ontologies/subjects/drug-discovery
148 sg:ontologies/subjects/ecology
149 sg:ontologies/subjects/evolution
150 sg:ontologies/subjects/genetics
151 sg:ontologies/subjects/immunology
152 sg:ontologies/subjects/microbiology
153 sg:ontologies/subjects/molecular-biology
154 sg:ontologies/subjects/neuroscience
155 sg:ontologies/subjects/physiology
156 sg:ontologies/subjects/plant-sciences
157 sg:ontologies/subjects/psychology
158 sg:ontologies/subjects/stem-cells
159 sg:ontologies/subjects/structural-biology
160 sg:ontologies/subjects/systems-biology
161 sg:ontologies/subjects/zoology
162 skos:prefLabel Biological sciences
163 skos:topConceptOf sg:ontologies/subjects/
164 sg:ontologies/subjects/bone-marrow-transplantation sgo:sdDataset onto_subjects
165 rdf:type npg:Subject
166 skos:Concept
167 rdfs:label Bone marrow transplantation
168 skos:altLabel Bone Marrow Cell Transplantation
169 skos:broader sg:ontologies/subjects/immunology
170 skos:definition Bone marrow transplantation is the transference of bone marrow from one human or animal to another for a variety of purposes. Bone marrow transplantation can be used to treat certain blood disorders such as leukemia or immunodeficiency, but can also have serious complications such as graft-versus-host disease.
171 skos:inScheme sg:ontologies/subjects/
172 skos:prefLabel Bone marrow transplantation
173 sg:ontologies/subjects/cell-death-and-immune-response sgo:sdDataset onto_subjects
174 rdf:type npg:Subject
175 skos:Concept
176 rdfs:label Cell death and immune response
177 skos:altLabel Cell Death
178 Immune response
179 skos:broader sg:ontologies/subjects/immunology
180 skos:definition Cell death is a process by which a cell's vital capacity is terminated. During an immune response, cells of the immune system cause the death of cells that are infected with microorganisms or are otherwise abnormal and remove dead cell fragments from the body. Failure to remove dead cells can cause inflammatory disease.
181 skos:inScheme sg:ontologies/subjects/
182 skos:prefLabel Cell death and immune response
183 sg:ontologies/subjects/chemokines sgo:sdDataset onto_subjects
184 rdf:type npg:Subject
185 skos:Concept
186 rdfs:label Chemokines
187 skos:altLabel Chemotactic Cytokines
188 Intercrines
189 skos:broader sg:ontologies/subjects/cytokines
190 sg:ontologies/subjects/immunology
191 skos:definition Chemokines are a class of cytokine protein that act as signalling molecules, regulating immune and inflammatory responses; for example, modulating cell migration properties and localization of target cells such as leucokytes. The biological functions of chemokines are typically mediated by signalling through G protein-coupled chemokine receptors.
192 skos:inScheme sg:ontologies/subjects/
193 skos:prefLabel Chemokines
194 sg:ontologies/subjects/coagulation-system sgo:sdDataset onto_subjects
195 rdf:type npg:Subject
196 skos:Concept
197 rdfs:label Coagulation system
198 skos:broader sg:ontologies/subjects/immunology
199 skos:definition The coagulation system is composed of cells, proteins and processes that mediate blood clotting. Damage to a blood vessel wall triggers the system, initiating interactions between platelets and blood coagulation factors. This leads to the formation of a fibrin-containing clot, which stops bleeding and initiates vessel repair.
200 skos:inScheme sg:ontologies/subjects/
201 skos:prefLabel Coagulation system
202 sg:ontologies/subjects/complement-cascade sgo:sdDataset onto_subjects
203 rdf:type npg:Subject
204 skos:Concept
205 rdfs:label Complement cascade
206 skos:altLabel Complement pathway
207 skos:broader sg:ontologies/subjects/immunology
208 skos:definition The complement cascade is a biochemical process in the blood that helps or 'complements' cells of the immune system to eliminate invading pathogens. When activated by one of three pathways, a cascade of serial cleavage events results in a marked amplification of the immune response and formation of the cell-killing membrane attack complex.
209 skos:inScheme sg:ontologies/subjects/
210 skos:prefLabel Complement cascade
211 sg:ontologies/subjects/cytokines sgo:sdDataset onto_subjects
212 rdf:type npg:Subject
213 skos:Concept
214 rdfs:label Cytokines
215 skos:broader sg:ontologies/subjects/biochemistry
216 sg:ontologies/subjects/immunology
217 skos:definition Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes that regulate immune responses, haematopoiesis and lymphocyte development. Cytokines include interleukins, chemokines and other signalling molecules. Each cytokine acts through its own receptor on target cells, and these receptors include members of the immunoglobulin (Ig) superfamily and tumour necrosis factor (TNF).
218 skos:inScheme sg:ontologies/subjects/
219 skos:narrower sg:ontologies/subjects/autocrine-motility-factor
220 sg:ontologies/subjects/chemokines
221 sg:ontologies/subjects/haematopoietic-cell-growth-factors
222 sg:ontologies/subjects/hepatocyte-growth-factor
223 sg:ontologies/subjects/interferons
224 sg:ontologies/subjects/interleukins
225 sg:ontologies/subjects/leukaemia-inhibitory-factor
226 sg:ontologies/subjects/lymphokines
227 sg:ontologies/subjects/monokines
228 sg:ontologies/subjects/oncostatin-m
229 sg:ontologies/subjects/osteopontin
230 sg:ontologies/subjects/transforming-growth-factor-beta
231 sg:ontologies/subjects/tumour-necrosis-factors
232 skos:prefLabel Cytokines
233 sg:ontologies/subjects/gene-regulation-in-immune-cells sgo:sdDataset onto_subjects
234 rdf:type npg:Subject
235 skos:Concept
236 rdfs:label Gene regulation in immune cells
237 skos:broader sg:ontologies/subjects/immunology
238 skos:definition Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products.
239 skos:inScheme sg:ontologies/subjects/
240 skos:narrower sg:ontologies/subjects/epigenetics-in-immune-cells
241 sg:ontologies/subjects/immunogenetics
242 sg:ontologies/subjects/mirna-in-immune-cells
243 skos:prefLabel Gene regulation in immune cells
244 sg:ontologies/subjects/haematopoiesis sgo:sdDataset onto_subjects
245 rdf:type npg:Subject
246 skos:Concept
247 rdfs:label Haematopoiesis
248 skos:altLabel Medullary Hematopoiesis
249 skos:broader sg:ontologies/subjects/developmental-biology
250 sg:ontologies/subjects/immunology
251 skos:definition Haematopoiesis refers to the commitment and differentiation processes that lead to the formation of all blood cells from haematopoietic stem cells. In adults, haematopoiesis occurs mainly in the bone marrow (medullary), but it can also occur in other tissues such as the liver, thymus and spleen (extramedullary).
252 skos:inScheme sg:ontologies/subjects/
253 skos:narrower sg:ontologies/subjects/erythropoiesis
254 sg:ontologies/subjects/leukopoiesis
255 sg:ontologies/subjects/lymphopoiesis
256 sg:ontologies/subjects/myelopoiesis
257 sg:ontologies/subjects/thrombopoiesis
258 skos:prefLabel Haematopoiesis
259 sg:ontologies/subjects/imaging-the-immune-system sgo:sdDataset onto_subjects
260 rdf:type npg:Subject
261 skos:Concept
262 rdfs:label Imaging the immune system
263 skos:broader sg:ontologies/subjects/immunology
264 skos:definition Imaging the immune system involves a set of methods and analytical tools that are used to visualize immune responses at the cellular level as they occur in their native environment in real time.
265 skos:inScheme sg:ontologies/subjects/
266 skos:prefLabel Imaging the immune system
267 sg:ontologies/subjects/immune-cell-death sgo:sdDataset onto_subjects
268 rdf:type npg:Subject
269 skos:Concept
270 rdfs:label Immune cell death
271 skos:altLabel Cell Death
272 skos:broader sg:ontologies/subjects/immunology
273 skos:definition Immune cell death is the process by which an immune cell undergoes cell death. There are various types of cell death mediated by intracellular programmes or external factors including apoptosis, necrosis, pyroptosis and necroptosis.
274 skos:inScheme sg:ontologies/subjects/
275 skos:prefLabel Immune cell death
276 sg:ontologies/subjects/immune-evasion sgo:sdDataset onto_subjects
277 rdf:type npg:Subject
278 skos:Concept
279 rdfs:label Immune evasion
280 skos:altLabel Immune Evasions
281 skos:broader sg:ontologies/subjects/immunology
282 skos:definition Immune evasion is a strategy used by pathogenic organisms and tumours to evade a host's immune response to maximize their probability of being transmitted to a fresh host or to continue growing, respectively.
283 skos:inScheme sg:ontologies/subjects/
284 skos:prefLabel Immune evasion
285 sg:ontologies/subjects/immunogenetics sgo:sdDataset onto_subjects
286 rdf:type npg:Subject
287 skos:Concept
288 rdfs:label Immunogenetics
289 skos:altLabel Immunogenetic
290 skos:broader sg:ontologies/subjects/gene-regulation-in-immune-cells
291 sg:ontologies/subjects/genetics
292 sg:ontologies/subjects/immunology
293 skos:definition Immunogenetics is the study of the genetic basis of the immune response. It includes the study of normal immunological pathways and the identification of genetic variations that result in immune defects, which may result in the identification of new therapeutic targets for immune diseases.
294 skos:inScheme sg:ontologies/subjects/
295 skos:prefLabel Immunogenetics
296 sg:ontologies/subjects/immunological-disorders sgo:sdDataset onto_subjects
297 rdf:type npg:Subject
298 skos:Concept
299 rdfs:label Immunological disorders
300 skos:altLabel Diseases of Immune System
301 Immune Disease
302 Immune Diseases
303 Immune Disorder
304 Immune Disorders
305 Immune System Disease
306 Immune System Diseases
307 Immunologic Disease
308 Immunologic Diseases
309 Immunological Disease
310 Immunological Diseases
311 skos:broader sg:ontologies/subjects/diseases
312 sg:ontologies/subjects/immunology
313 skos:definition Immunological disorders are diseases or conditions caused by a dysfunction of the immune system and include allergy, asthma, autoimmune diseases, autoinflammatory syndromes and immunological deficiency syndromes.
314 skos:inScheme sg:ontologies/subjects/
315 skos:narrower sg:ontologies/subjects/autoimmune-diseases
316 sg:ontologies/subjects/graft-versus-host-disease
317 sg:ontologies/subjects/immunological-deficiency-syndromes
318 sg:ontologies/subjects/immunoproliferative-disorders
319 sg:ontologies/subjects/inflammatory-diseases
320 sg:ontologies/subjects/lymphoproliferative-disorders
321 sg:ontologies/subjects/primary-immunodeficiency-disorders
322 sg:ontologies/subjects/thrombocytopaenic-purpura
323 skos:prefLabel Immunological disorders
324 sg:ontologies/subjects/immunotherapy sgo:sdDataset onto_subjects
325 rdf:type npg:Subject
326 skos:Concept
327 rdfs:label Immunotherapy
328 skos:altLabel Immunotherapies
329 skos:broader sg:ontologies/subjects/immunology
330 sg:ontologies/subjects/therapeutics
331 skos:definition Immunotherapy is the treatment of disease by inducing, enhancing or suppressing an immune response. Activation immunotherapies induce or amplify an immune response and are used in vaccines and as cancer immunotherapies. Suppression immunotherapies reduce or suppress an immune response and are used to prevent graft rejection and treat autoimmunity and allergy.
332 skos:inScheme sg:ontologies/subjects/
333 skos:narrower sg:ontologies/subjects/immunization
334 sg:ontologies/subjects/immunosuppression
335 skos:prefLabel Immunotherapy
336 sg:ontologies/subjects/infection sgo:sdDataset onto_subjects
337 rdf:type npg:Subject
338 skos:Concept
339 rdfs:label Infection
340 skos:broader sg:ontologies/subjects/immunology
341 sg:ontologies/subjects/pathogenesis
342 skos:definition Infection is the invasion by and multiplication of 'foreign' microorganisms that can cause pathological conditions or diseases in the host organism.
343 skos:inScheme sg:ontologies/subjects/
344 skos:prefLabel Infection
345 sg:ontologies/subjects/infectious-diseases sgo:sdDataset onto_subjects
346 rdf:type npg:Subject
347 skos:Concept
348 rdfs:label Infectious diseases
349 skos:altLabel Communicable Disease
350 Communicable Diseases
351 skos:broader sg:ontologies/subjects/diseases
352 sg:ontologies/subjects/immunology
353 skos:definition Infectious diseases – also known as contagious diseases, transmissible diseases or communicable diseases – are caused by pathogenic microorganisms that infect a host organism and can be spread, directly or indirectly, from one organism to another.
354 skos:inScheme sg:ontologies/subjects/
355 skos:narrower sg:ontologies/subjects/bacterial-infection
356 sg:ontologies/subjects/clostridium-difficile
357 sg:ontologies/subjects/fungal-infection
358 sg:ontologies/subjects/helicobacter-pylori
359 sg:ontologies/subjects/hepatitis
360 sg:ontologies/subjects/hiv-infections
361 sg:ontologies/subjects/influenza-virus
362 sg:ontologies/subjects/listeria
363 sg:ontologies/subjects/malaria
364 sg:ontologies/subjects/meningitis
365 sg:ontologies/subjects/neonatal-sepsis
366 sg:ontologies/subjects/parasitic-infection
367 sg:ontologies/subjects/tuberculosis
368 sg:ontologies/subjects/viral-infection
369 skos:prefLabel Infectious diseases
370 sg:ontologies/subjects/inflammation sgo:sdDataset onto_subjects
371 rdf:type npg:Subject
372 skos:Concept
373 rdfs:label Inflammation
374 skos:altLabel Inflammations
375 skos:broader sg:ontologies/subjects/immunology
376 sg:ontologies/subjects/pathogenesis
377 skos:definition Inflammation is a biological response to harmful stimuli, such as pathogens, damaged cells or irradiation. It is a protective attempt by the organism to remove injurious stimuli and to initiate the healing process. It is characterized by pain, redness, heat, swelling and disturbance of function.
378 skos:inScheme sg:ontologies/subjects/
379 skos:narrower sg:ontologies/subjects/acute-inflammation
380 sg:ontologies/subjects/chronic-inflammation
381 sg:ontologies/subjects/inflammasome
382 sg:ontologies/subjects/sepsis
383 skos:prefLabel Inflammation
384 sg:ontologies/subjects/innate-immune-cells sgo:sdDataset onto_subjects
385 rdf:type npg:Subject
386 skos:Concept
387 rdfs:label Innate immune cells
388 skos:broader sg:ontologies/subjects/immunology
389 skos:definition Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and NK cells.
390 skos:inScheme sg:ontologies/subjects/
391 skos:narrower sg:ontologies/subjects/dendritic-cells
392 sg:ontologies/subjects/granulocytes
393 sg:ontologies/subjects/innate-lymphoid-cells
394 sg:ontologies/subjects/monocytes-and-macrophages
395 skos:prefLabel Innate immune cells
396 sg:ontologies/subjects/innate-immunity sgo:sdDataset onto_subjects
397 rdf:type npg:Subject
398 skos:Concept
399 rdfs:label Innate immunity
400 skos:altLabel Disease Resistance
401 Innate Immune Response
402 Innate Immune Responses
403 Native Immunity
404 Natural Immunity
405 Natural Resistance
406 Non-Specific Immunity
407 Non-specific immunity
408 skos:broader sg:ontologies/subjects/immunology
409 sg:ontologies/subjects/immunopathogenesis
410 skos:definition Innate immunity is an immunological subsystem that comprises the cells and mechanisms that provide the first line of defence from infection in a non-specific manner. Innate immune responses are rapid and independent of antigen. Innate immune systems are found in all classes of plants and animals.
411 skos:inScheme sg:ontologies/subjects/
412 skos:narrower sg:ontologies/subjects/pattern-recognition-receptors
413 skos:prefLabel Innate immunity
414 sg:ontologies/subjects/lymphatic-system sgo:sdDataset onto_subjects
415 rdf:type npg:Subject
416 skos:Concept
417 rdfs:label Lymphatic system
418 skos:altLabel Lymphatic Systems
419 skos:broader sg:ontologies/subjects/immunology
420 skos:definition The lymphatic system is a network of lymphoid organs and lymphatic vessels. It transports lymph fluid and helps to clear toxins and other waste from the body’s tissues. Lymphocytes use the lymphatic system to circulate throughout the body, but it can also facilitate the spread of cancer cells.
421 skos:inScheme sg:ontologies/subjects/
422 skos:narrower sg:ontologies/subjects/lymphangiogenesis
423 sg:ontologies/subjects/lymphatic-vessels
424 skos:prefLabel Lymphatic system
425 sg:ontologies/subjects/lymphocytes sgo:sdDataset onto_subjects
426 rdf:type npg:Subject
427 skos:Concept
428 rdfs:label Lymphocytes
429 skos:altLabel Lymphoid Cells
430 skos:broader sg:ontologies/subjects/immunology
431 skos:definition Lymphocytes are white blood cells that have important immune functions. The main populations of lymphocytes are B cells, T cells and natural killer (NK) cells. They are typically (although not exclusively) associated with adaptive immune responses. Populations of novel innate-like lymphocytes were first described in 2010.
432 skos:inScheme sg:ontologies/subjects/
433 skos:narrower sg:ontologies/subjects/b-cells
434 sg:ontologies/subjects/nk-cells
435 sg:ontologies/subjects/t-cells
436 skos:prefLabel Lymphocytes
437 sg:ontologies/subjects/lymphoid-tissues sgo:sdDataset onto_subjects
438 rdf:type npg:Subject
439 skos:Concept
440 rdfs:label Lymphoid tissues
441 skos:altLabel Lymphatic Tissue
442 Lymphatic Tissues
443 Lymphoid Tissue
444 skos:broader sg:ontologies/subjects/immunology
445 skos:definition Lymphoid tissues are organized structures that support immune responses. The bone marrow and thymus are primary lymphoid tissues and the sites of lymphocyte development. The lymph nodes, spleen, tonsils and Peyer’s patches are examples of secondary lymphoid tissue. Chronic inflammation can lead to the development of tertiary lymphoid tissue.
446 skos:inScheme sg:ontologies/subjects/
447 skos:narrower sg:ontologies/subjects/bone-marrow
448 sg:ontologies/subjects/lymph-node
449 sg:ontologies/subjects/spleen
450 sg:ontologies/subjects/thymus
451 sg:ontologies/subjects/tonsils
452 skos:prefLabel Lymphoid tissues
453 sg:ontologies/subjects/mucosal-immunology sgo:sdDataset onto_subjects
454 rdf:type npg:Subject
455 skos:Concept
456 rdfs:label Mucosal immunology
457 skos:broader sg:ontologies/subjects/immunology
458 skos:definition Mucosal immunology is the study of immune responses that occur at mucosal surfaces, such as the intestines, the urogenital tract and the lungs. These tissues are closely associated with the external environment and the mucosal immune system must provide protective immunity to pathogens but remain tolerant of non-harmful environmental substances.
459 skos:inScheme sg:ontologies/subjects/
460 skos:prefLabel Mucosal immunology
461 sg:ontologies/subjects/neuroimmunology sgo:sdDataset onto_subjects
462 rdf:type npg:Subject
463 skos:Concept
464 rdfs:label Neuroimmunology
465 skos:broader sg:ontologies/subjects/immunology
466 sg:ontologies/subjects/neuroscience
467 skos:definition Neuroimmunology is a field that studies the interaction of the immune and nervous systems.
468 skos:inScheme sg:ontologies/subjects/
469 skos:prefLabel Neuroimmunology
470 sg:ontologies/subjects/osteoimmunology sgo:sdDataset onto_subjects
471 rdf:type npg:Subject
472 skos:Concept
473 rdfs:label Osteoimmunology
474 skos:broader sg:ontologies/subjects/immunology
475 sg:ontologies/subjects/rheumatology
476 skos:definition Osteoimmunology is the study of how the immune and skeletal systems interact.
477 skos:inScheme sg:ontologies/subjects/
478 skos:prefLabel Osteoimmunology
479 sg:ontologies/subjects/plant-immunology sgo:sdDataset onto_subjects
480 rdf:type npg:Subject
481 skos:Concept
482 rdfs:label Plant immunology
483 skos:broader sg:ontologies/subjects/immunology
484 skos:definition Plant immunology is the study of how plants defend their tissues from infection. Plants do not have an adaptive immune system, but have evolved innate immune mechanisms (including the resistance proteins) to sense and respond to infections.
485 skos:inScheme sg:ontologies/subjects/
486 skos:prefLabel Plant immunology
487 sg:ontologies/subjects/signal-transduction sgo:sdDataset onto_subjects
488 rdf:type npg:Subject
489 skos:Concept
490 rdfs:label Signal transduction
491 skos:altLabel Receptor Mediated Signal Transduction
492 Receptor-Mediated Signal Transduction
493 Receptor-Mediated Signal Transductions
494 Signal Pathway
495 Signal Pathways
496 Signal Transduction Pathway
497 Signal Transduction Pathways
498 Signal Transduction System
499 Signal Transduction Systems
500 Signal Transductions
501 skos:broader sg:ontologies/subjects/immunology
502 skos:inScheme sg:ontologies/subjects/
503 skos:narrower sg:ontologies/subjects/nf-kappab
504 skos:prefLabel Signal transduction
505 sg:ontologies/subjects/translational-immunology sgo:sdDataset onto_subjects
506 rdf:type npg:Subject
507 skos:Concept
508 rdfs:label Translational immunology
509 skos:broader sg:ontologies/subjects/immunology
510 skos:definition Translational immunology is the process by which researchers use immunological discoveries to develop practical solutions for human problems. Examples include the development of vaccines against infectious diseases or the engineering of new types of drugs to treat inflammatory disorders.
511 skos:inScheme sg:ontologies/subjects/
512 skos:prefLabel Translational immunology
513 sg:ontologies/subjects/transplant-immunology sgo:sdDataset onto_subjects
514 rdf:type npg:Subject
515 skos:Concept
516 rdfs:label Transplant immunology
517 skos:altLabel Transplantation Immunology
518 skos:broader sg:ontologies/subjects/immunology
519 skos:definition Transplant immunology is the study of the immune response that occurs when an organ or tissue is moved (grafted) from one individual to another. A major problem following transplantation is that the immune system of the recipient sees the grafted tissue as ‘foreign’ and attacks and destroys it.
520 skos:inScheme sg:ontologies/subjects/
521 skos:narrower sg:ontologies/subjects/allograft
522 sg:ontologies/subjects/autograft
523 skos:prefLabel Transplant immunology
524 sg:ontologies/subjects/tumour-immunology sgo:sdDataset onto_subjects
525 rdf:type npg:Subject
526 skos:Concept
527 rdfs:label Tumour immunology
528 skos:broader sg:ontologies/subjects/cancer
529 sg:ontologies/subjects/immunology
530 skos:definition Tumour immunology describes the interaction between cells of the immune system with tumour cells. Understanding these interactions is important for the development of new therapies for cancer treatment.
531 skos:inScheme sg:ontologies/subjects/
532 skos:narrower sg:ontologies/subjects/immunosurveillance
533 skos:prefLabel Tumour immunology
534 sg:ontologies/subjects/vaccines sgo:sdDataset onto_subjects
535 rdf:type npg:Subject
536 skos:Concept
537 rdfs:label Vaccines
538 skos:broader sg:ontologies/subjects/applied-immunology
539 sg:ontologies/subjects/immunology
540 sg:ontologies/subjects/microbiology
541 skos:definition Vaccines are a clinical product that is composed of live or dead material from an infectious agent – bacterium, virus, fungus or parasite – that elicit protective immunity against the pathogen when administered. These substances are used to prevent the spread of infectious diseases.
542 skos:inScheme sg:ontologies/subjects/
543 skos:narrower sg:ontologies/subjects/adjuvants
544 sg:ontologies/subjects/cell-vaccines
545 sg:ontologies/subjects/conjugate-vaccines
546 sg:ontologies/subjects/dna-vaccines
547 sg:ontologies/subjects/inactivated-vaccines
548 sg:ontologies/subjects/live-attenuated-vaccines
549 sg:ontologies/subjects/peptide-vaccines
550 sg:ontologies/subjects/protein-vaccines
551 sg:ontologies/subjects/rna-vaccines
552 skos:prefLabel Vaccines
553 skos:Concept sgo:sdDataset for_codes
554 rdf:type rdfs:Class
555 rdfs:Resource
556 rdfs:subClassOf rdfs:Resource
557 skos:Concept
 




Preview window. Press ESC to close (or click here)


...