Double-strand DNA breaks


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Double-strand DNA breaks

DESCRIPTION

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can promote potentially lethal chromosomal rearrangements, and can be repaired by homologous recombination (HR) or non-homologous-end joining (NHEJ).

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/double-strand-dna-breaks'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/double-strand-dna-breaks'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/double-strand-dna-breaks'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/double-strand-dna-breaks'


 

This table displays all metadata directly associated to this object as RDF triples.

64 TRIPLES      9 PREDICATES      16 URIs      10 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/double-strand-dna-breaks sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Double-strand DNA breaks
6 skos:altLabel Double Strand DNA Breaks
7 Double Stranded DNA Break
8 Double Stranded DNA Breaks
9 Double-Strand DNA Break
10 Double-Stranded DNA Break
11 Double-Stranded DNA Breaks
12 skos:broader sg:ontologies/subjects/dna-damage-and-repair
13 skos:definition A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can promote potentially lethal chromosomal rearrangements, and can be repaired by homologous recombination (HR) or non-homologous-end joining (NHEJ).
14 skos:inScheme sg:ontologies/subjects/
15 skos:prefLabel Double-strand DNA breaks
16 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
17 dcterms:title Nature Subjects Taxonomy
18 sgo:sdDataset onto_subjects
19 rdf:type skos:ConceptScheme
20 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
21 sg:ontologies/subjects/biological-sciences
22 sg:ontologies/subjects/business-and-commerce
23 sg:ontologies/subjects/earth-and-environmental-sciences
24 sg:ontologies/subjects/health-sciences
25 sg:ontologies/subjects/humanities
26 sg:ontologies/subjects/physical-sciences
27 sg:ontologies/subjects/scientific-community-and-society
28 sg:ontologies/subjects/social-science
29 sg:ontologies/subjects/dna-damage-and-repair sgo:sdDataset onto_subjects
30 rdf:type npg:Subject
31 skos:Concept
32 rdfs:label DNA damage and repair
33 skos:altLabel Base Excision Repair
34 Base Excision Repairs
35 DNA Damage
36 DNA Damages
37 DNA Injuries
38 DNA Injury
39 Excision Repair
40 Excision Repairs
41 Genotoxic Stress
42 Genotoxic Stresses
43 Nucleotide Excision Repair
44 Nucleotide Excision Repairs
45 skos:broader sg:ontologies/subjects/molecular-biology
46 skos:definition DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce mutations if not corrected, multiple cellular DNA repair mechanisms exist to remove damaged regions of chromosomes to prevent these potentially deleterious effects.
47 skos:inScheme sg:ontologies/subjects/
48 skos:narrower sg:ontologies/subjects/base-excision-repair
49 sg:ontologies/subjects/dna-adducts
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51 sg:ontologies/subjects/dna-damage-response
52 sg:ontologies/subjects/dna-mismatch-repair
53 sg:ontologies/subjects/double-strand-dna-breaks
54 sg:ontologies/subjects/homologous-recombination
55 sg:ontologies/subjects/non-homologous-end-joining
56 sg:ontologies/subjects/nucleotide-excision-repair
57 sg:ontologies/subjects/single-strand-dna-breaks
58 sg:ontologies/subjects/translesion-synthesis
59 skos:prefLabel DNA damage and repair
60 skos:Concept sgo:sdDataset for_codes
61 rdf:type rdfs:Class
62 rdfs:Resource
63 rdfs:subClassOf rdfs:Resource
64 skos:Concept
 




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