Dosage compensation


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Dosage compensation

DESCRIPTION

Dosage compensation is a process that balances expression of sex-linked and autosomal genes in the heterogametic sex. For example, one X chromosome in XX female mammals is randomly inactivated in every cell, and gene transcription levels from the X chromosome of XO or XY male Drosophila is elevated to approximately equal the output of two sex chromosomes in XX females.

Broader Concepts

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HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/dosage-compensation'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/dosage-compensation'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/dosage-compensation'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/dosage-compensation'


 

This table displays all metadata directly associated to this object as RDF triples.

50 TRIPLES      9 PREDICATES      17 URIs      11 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/dosage-compensation sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Dosage compensation
6 skos:altLabel Dosage Compensation (Genetics)
7 Gene Dosage Compensation
8 Gene Dosage Compensations
9 Genetic Dosage Compensation
10 Genetic Dosage Compensations
11 X Chromosome Hypertranscription
12 X-Chromosome Hypertranscription
13 skos:broader sg:ontologies/subjects/epigenetics
14 skos:definition Dosage compensation is a process that balances expression of sex-linked and autosomal genes in the heterogametic sex. For example, one X chromosome in XX female mammals is randomly inactivated in every cell, and gene transcription levels from the X chromosome of XO or XY male Drosophila is elevated to approximately equal the output of two sex chromosomes in XX females.
15 skos:inScheme sg:ontologies/subjects/
16 skos:prefLabel Dosage compensation
17 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
18 dcterms:title Nature Subjects Taxonomy
19 sgo:sdDataset onto_subjects
20 rdf:type skos:ConceptScheme
21 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
22 sg:ontologies/subjects/biological-sciences
23 sg:ontologies/subjects/business-and-commerce
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30 sg:ontologies/subjects/epigenetics sgo:sdDataset onto_subjects
31 rdf:type npg:Subject
32 skos:Concept
33 rdfs:label Epigenetics
34 skos:altLabel Epigenetic
35 Epigenomic
36 Epigenomics
37 skos:broader sg:ontologies/subjects/genetics
38 sg:ontologies/subjects/molecular-biology
39 skos:definition Epigenetics is the study of molecular processes that influence the flow of information between a constant DNA sequence and variable gene expression patterns. This includes investigation of nuclear organization, DNA methylation, histone modification and RNA transcription. Epigenetic processes can result in intergenerational (heritable) effects as well as clonal propagation of cell identity without any mutational change in DNA sequence.
40 skos:inScheme sg:ontologies/subjects/
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42 sg:ontologies/subjects/dosage-compensation
43 sg:ontologies/subjects/gene-silencing
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46 skos:Concept sgo:sdDataset for_codes
47 rdf:type rdfs:Class
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50 skos:Concept
 




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