DNA methylation


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

DNA methylation

DESCRIPTION

DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine donor and can lead to mitotic propagation of the modified sequence with consequences for the binding of regulatory proteins such as transcription factors.

Broader Concepts

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/dna-methylation'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/dna-methylation'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/dna-methylation'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/dna-methylation'


 

This table displays all metadata directly associated to this object as RDF triples.

44 TRIPLES      9 PREDICATES      11 URIs      5 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/dna-methylation sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label DNA methylation
6 skos:altLabel DNA Methylations
7 skos:broader sg:ontologies/subjects/epigenetics
8 skos:definition DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine donor and can lead to mitotic propagation of the modified sequence with consequences for the binding of regulatory proteins such as transcription factors.
9 skos:inScheme sg:ontologies/subjects/
10 skos:prefLabel DNA methylation
11 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
12 dcterms:title Nature Subjects Taxonomy
13 sgo:sdDataset onto_subjects
14 rdf:type skos:ConceptScheme
15 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
16 sg:ontologies/subjects/biological-sciences
17 sg:ontologies/subjects/business-and-commerce
18 sg:ontologies/subjects/earth-and-environmental-sciences
19 sg:ontologies/subjects/health-sciences
20 sg:ontologies/subjects/humanities
21 sg:ontologies/subjects/physical-sciences
22 sg:ontologies/subjects/scientific-community-and-society
23 sg:ontologies/subjects/social-science
24 sg:ontologies/subjects/epigenetics sgo:sdDataset onto_subjects
25 rdf:type npg:Subject
26 skos:Concept
27 rdfs:label Epigenetics
28 skos:altLabel Epigenetic
29 Epigenomic
30 Epigenomics
31 skos:broader sg:ontologies/subjects/genetics
32 sg:ontologies/subjects/molecular-biology
33 skos:definition Epigenetics is the study of molecular processes that influence the flow of information between a constant DNA sequence and variable gene expression patterns. This includes investigation of nuclear organization, DNA methylation, histone modification and RNA transcription. Epigenetic processes can result in intergenerational (heritable) effects as well as clonal propagation of cell identity without any mutational change in DNA sequence.
34 skos:inScheme sg:ontologies/subjects/
35 skos:narrower sg:ontologies/subjects/dna-methylation
36 sg:ontologies/subjects/dosage-compensation
37 sg:ontologies/subjects/gene-silencing
38 sg:ontologies/subjects/imprinting
39 skos:prefLabel Epigenetics
40 skos:Concept sgo:sdDataset for_codes
41 rdf:type rdfs:Class
42 rdfs:Resource
43 rdfs:subClassOf rdfs:Resource
44 skos:Concept
 




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