DNA damage response


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

DNA damage response

DESCRIPTION

The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage, to prevent the generation of potentially deleterious mutations.

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-response'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-response'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-response'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-response'


 

This table displays all metadata directly associated to this object as RDF triples.

58 TRIPLES      8 PREDICATES      10 URIs      4 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/dna-damage-response sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label DNA damage response
6 skos:broader sg:ontologies/subjects/dna-damage-and-repair
7 skos:definition The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage, to prevent the generation of potentially deleterious mutations.
8 skos:inScheme sg:ontologies/subjects/
9 skos:prefLabel DNA damage response
10 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
11 dcterms:title Nature Subjects Taxonomy
12 sgo:sdDataset onto_subjects
13 rdf:type skos:ConceptScheme
14 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
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23 sg:ontologies/subjects/dna-damage-and-repair sgo:sdDataset onto_subjects
24 rdf:type npg:Subject
25 skos:Concept
26 rdfs:label DNA damage and repair
27 skos:altLabel Base Excision Repair
28 Base Excision Repairs
29 DNA Damage
30 DNA Damages
31 DNA Injuries
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35 Genotoxic Stress
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37 Nucleotide Excision Repair
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39 skos:broader sg:ontologies/subjects/molecular-biology
40 skos:definition DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce mutations if not corrected, multiple cellular DNA repair mechanisms exist to remove damaged regions of chromosomes to prevent these potentially deleterious effects.
41 skos:inScheme sg:ontologies/subjects/
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54 skos:Concept sgo:sdDataset for_codes
55 rdf:type rdfs:Class
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57 rdfs:subClassOf rdfs:Resource
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