DNA damage checkpoints


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

DNA damage checkpoints

DESCRIPTION

A DNA damage checkpoint is a pause in the cell cycle that is induced in response to DNA damage to ensure that the damage is repaired before cell division resumes. Proteins that accumulate at the damage site typically activate the checkpoint and halt cell growth at the G1/S or G2/M boundaries.

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-checkpoints'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-checkpoints'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-checkpoints'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/dna-damage-checkpoints'


 

This table displays all metadata directly associated to this object as RDF triples.

58 TRIPLES      8 PREDICATES      10 URIs      4 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/dna-damage-checkpoints sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label DNA damage checkpoints
6 skos:broader sg:ontologies/subjects/dna-damage-and-repair
7 skos:definition A DNA damage checkpoint is a pause in the cell cycle that is induced in response to DNA damage to ensure that the damage is repaired before cell division resumes. Proteins that accumulate at the damage site typically activate the checkpoint and halt cell growth at the G1/S or G2/M boundaries.
8 skos:inScheme sg:ontologies/subjects/
9 skos:prefLabel DNA damage checkpoints
10 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
11 dcterms:title Nature Subjects Taxonomy
12 sgo:sdDataset onto_subjects
13 rdf:type skos:ConceptScheme
14 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
15 sg:ontologies/subjects/biological-sciences
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22 sg:ontologies/subjects/social-science
23 sg:ontologies/subjects/dna-damage-and-repair sgo:sdDataset onto_subjects
24 rdf:type npg:Subject
25 skos:Concept
26 rdfs:label DNA damage and repair
27 skos:altLabel Base Excision Repair
28 Base Excision Repairs
29 DNA Damage
30 DNA Damages
31 DNA Injuries
32 DNA Injury
33 Excision Repair
34 Excision Repairs
35 Genotoxic Stress
36 Genotoxic Stresses
37 Nucleotide Excision Repair
38 Nucleotide Excision Repairs
39 skos:broader sg:ontologies/subjects/molecular-biology
40 skos:definition DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce mutations if not corrected, multiple cellular DNA repair mechanisms exist to remove damaged regions of chromosomes to prevent these potentially deleterious effects.
41 skos:inScheme sg:ontologies/subjects/
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53 skos:prefLabel DNA damage and repair
54 skos:Concept sgo:sdDataset for_codes
55 rdf:type rdfs:Class
56 rdfs:Resource
57 rdfs:subClassOf rdfs:Resource
58 skos:Concept
 




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