DNA-binding proteins


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

DNA-binding proteins

DESCRIPTION

DNA-binding proteins are proteins that bind to single- or double-stranded DNA, generally in the major groove if the binding is sequence-specific – as with transcription factors that regulate expression of genes, and nucleases that cleave DNA between nucleotides. DNA-binding proteins can also bind DNA non-specifically, such as polymerases and histones.

Broader Concepts

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins", 
    "rdfs:label": "DNA-binding proteins", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "DNA-binding protein"
      }, 
      {
        "@language": "en", 
        "@value": "Single Stranded DNA Binding Proteins"
      }, 
      {
        "@language": "en", 
        "@value": "Single-Stranded DNA-Binding Protein"
      }, 
      {
        "@language": "en", 
        "@value": "DNA Binding Protein"
      }, 
      {
        "@language": "en", 
        "@value": "SS DNA BP"
      }, 
      {
        "@language": "en", 
        "@value": "DNA Helix Destabilizing Proteins"
      }, 
      {
        "@language": "en", 
        "@value": "Single-Stranded DNA Binding Proteins"
      }, 
      {
        "@language": "en", 
        "@value": "DNA Single Stranded Binding Protein"
      }, 
      {
        "@language": "en", 
        "@value": "Deoxyribonucleic acid binding protein"
      }, 
      {
        "@language": "en", 
        "@value": "DNA Binding Proteins"
      }, 
      {
        "@language": "en", 
        "@value": "Deoxyribonucleic acid binding proteins"
      }, 
      {
        "@language": "en", 
        "@value": "DNA Single-Stranded Binding Protein"
      }, 
      {
        "@language": "en", 
        "@value": "Single Stranded DNA Binding Protein"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/proteins"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "DNA-binding proteins are proteins that bind to single- or double-stranded DNA, generally in the major groove if the binding is sequence-specific \u2013 as with transcription factors that regulate expression of genes, and nucleases that cleave DNA between nucleotides. DNA-binding proteins can also bind DNA non-specifically, such as polymerases and histones. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "DNA-binding proteins"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/proteins", 
    "rdfs:label": "Proteins", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Protein Gene Products"
      }, 
      {
        "@language": "en", 
        "@value": "Gene Proteins"
      }, 
      {
        "@language": "en", 
        "@value": "Protein"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biochemistry"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chemical-biology"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein\u2019s structure and function. Newly synthesized proteins can be modified by post-translational modification, altering its protein folding, stability and activity. Proteins often associate into protein\u2013protein interaction networks for function. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/scleroproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cell-cycle-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/membrane-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cytoskeletal-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/complement"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/rna-binding-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/ubiquitylated-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/cerebrospinal-fluid-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/gtp-binding-protein-regulators"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/ribosomal-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/selenium-binding-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/ubiquitins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/mitochondrial-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nucleotide-binding-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nucleases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/tumour-suppressor-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nuclear-receptors"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/intracellular-signalling-peptides-and-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/proteome"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chromatin"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lipoproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/g-protein-coupled-receptors"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/thioredoxins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/acetyltransferases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/glycoproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/metalloproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/blood-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/nucleoproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/methylases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/phosphoproteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/transcription-factors"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/chaperones"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/sumoylated-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/integrins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/carrier-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/colipases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/contractile-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/circadian-rhythm-signalling-peptides-and-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/oncogene-proteins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/phosphorylases"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/lectins"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/viral-proteins"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Proteins"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://www.w3.org/2004/02/skos/core#Concept", 
    "rdfs:subClassOf": [
      {
        "id": "http://www.w3.org/2004/02/skos/core#Concept"
      }, 
      {
        "id": "http://www.w3.org/2000/01/rdf-schema#Resource"
      }
    ], 
    "sdDataset": "for_codes", 
    "type": [
      "http://www.w3.org/2000/01/rdf-schema#Resource", 
      "http://www.w3.org/2000/01/rdf-schema#Class"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "dcterms:description": [
      {
        "@language": "en", 
        "@value": "The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature."
      }
    ], 
    "dcterms:title": [
      {
        "@language": "en", 
        "@value": "Nature Subjects Taxonomy"
      }
    ], 
    "id": "http://scigraph.springernature.com/ontologies/subjects/", 
    "sdDataset": "onto_subjects", 
    "skos:hasTopConcept": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/physical-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/DEPRECATED"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/business-and-commerce"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/humanities"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/social-science"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/health-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/scientific-community-and-society"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/earth-and-environmental-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#ConceptScheme"
    ]
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/dna-binding-proteins'


 

This table displays all metadata directly associated to this object as RDF triples.

95 TRIPLES      9 PREDICATES      23 URIs      17 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/dna-binding-proteins sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label DNA-binding proteins
6 skos:altLabel DNA Binding Protein
7 DNA Binding Proteins
8 DNA Helix Destabilizing Proteins
9 DNA Single Stranded Binding Protein
10 DNA Single-Stranded Binding Protein
11 DNA-binding protein
12 Deoxyribonucleic acid binding protein
13 Deoxyribonucleic acid binding proteins
14 SS DNA BP
15 Single Stranded DNA Binding Protein
16 Single Stranded DNA Binding Proteins
17 Single-Stranded DNA Binding Proteins
18 Single-Stranded DNA-Binding Protein
19 skos:broader sg:ontologies/subjects/proteins
20 skos:definition DNA-binding proteins are proteins that bind to single- or double-stranded DNA, generally in the major groove if the binding is sequence-specific – as with transcription factors that regulate expression of genes, and nucleases that cleave DNA between nucleotides. DNA-binding proteins can also bind DNA non-specifically, such as polymerases and histones.
21 skos:inScheme sg:ontologies/subjects/
22 skos:prefLabel DNA-binding proteins
23 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
24 dcterms:title Nature Subjects Taxonomy
25 sgo:sdDataset onto_subjects
26 rdf:type skos:ConceptScheme
27 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
28 sg:ontologies/subjects/biological-sciences
29 sg:ontologies/subjects/business-and-commerce
30 sg:ontologies/subjects/earth-and-environmental-sciences
31 sg:ontologies/subjects/health-sciences
32 sg:ontologies/subjects/humanities
33 sg:ontologies/subjects/physical-sciences
34 sg:ontologies/subjects/scientific-community-and-society
35 sg:ontologies/subjects/social-science
36 sg:ontologies/subjects/proteins sgo:sdDataset onto_subjects
37 rdf:type npg:Subject
38 skos:Concept
39 rdfs:label Proteins
40 skos:altLabel Gene Proteins
41 Protein
42 Protein Gene Products
43 skos:broader sg:ontologies/subjects/biochemistry
44 sg:ontologies/subjects/chemical-biology
45 skos:definition Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure and function. Newly synthesized proteins can be modified by post-translational modification, altering its protein folding, stability and activity. Proteins often associate into protein–protein interaction networks for function.
46 skos:inScheme sg:ontologies/subjects/
47 skos:narrower sg:ontologies/subjects/acetyltransferases
48 sg:ontologies/subjects/blood-proteins
49 sg:ontologies/subjects/carrier-proteins
50 sg:ontologies/subjects/cell-cycle-proteins
51 sg:ontologies/subjects/cerebrospinal-fluid-proteins
52 sg:ontologies/subjects/chaperones
53 sg:ontologies/subjects/chromatin
54 sg:ontologies/subjects/circadian-rhythm-signalling-peptides-and-proteins
55 sg:ontologies/subjects/colipases
56 sg:ontologies/subjects/complement
57 sg:ontologies/subjects/contractile-proteins
58 sg:ontologies/subjects/cytoskeletal-proteins
59 sg:ontologies/subjects/dna-binding-proteins
60 sg:ontologies/subjects/g-protein-coupled-receptors
61 sg:ontologies/subjects/glycoproteins
62 sg:ontologies/subjects/gtp-binding-protein-regulators
63 sg:ontologies/subjects/integrins
64 sg:ontologies/subjects/intracellular-signalling-peptides-and-proteins
65 sg:ontologies/subjects/lectins
66 sg:ontologies/subjects/lipoproteins
67 sg:ontologies/subjects/membrane-proteins
68 sg:ontologies/subjects/metalloproteins
69 sg:ontologies/subjects/methylases
70 sg:ontologies/subjects/mitochondrial-proteins
71 sg:ontologies/subjects/nuclear-receptors
72 sg:ontologies/subjects/nucleases
73 sg:ontologies/subjects/nucleoproteins
74 sg:ontologies/subjects/nucleotide-binding-proteins
75 sg:ontologies/subjects/oncogene-proteins
76 sg:ontologies/subjects/phosphoproteins
77 sg:ontologies/subjects/phosphorylases
78 sg:ontologies/subjects/proteome
79 sg:ontologies/subjects/ribosomal-proteins
80 sg:ontologies/subjects/rna-binding-proteins
81 sg:ontologies/subjects/scleroproteins
82 sg:ontologies/subjects/selenium-binding-proteins
83 sg:ontologies/subjects/sumoylated-proteins
84 sg:ontologies/subjects/thioredoxins
85 sg:ontologies/subjects/transcription-factors
86 sg:ontologies/subjects/tumour-suppressor-proteins
87 sg:ontologies/subjects/ubiquitins
88 sg:ontologies/subjects/ubiquitylated-proteins
89 sg:ontologies/subjects/viral-proteins
90 skos:prefLabel Proteins
91 skos:Concept sgo:sdDataset for_codes
92 rdf:type rdfs:Class
93 rdfs:Resource
94 rdfs:subClassOf rdfs:Resource
95 skos:Concept
 




Preview window. Press ESC to close (or click here)


...