Clinical epigenetics


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Clinical epigenetics

DESCRIPTION

Clinical epigenetics is the application of molecular biology techniques detecting alterations in DNA methylation or histone modification to diagnose or study disorders characterized by heritable defects in the expression of a gene or genome. Applications include Rett syndrome, disorders of imprinting, uniparental inheritance of chromosomes and chromosome segments, and somatic epigenetic anomalies in cancers.

Broader Concepts

Narrower Concepts

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/clinical-epigenetics'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/clinical-epigenetics'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/clinical-epigenetics'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/clinical-epigenetics'


 

This table displays all metadata directly associated to this object as RDF triples.

52 TRIPLES      9 PREDICATES      11 URIs      4 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/clinical-epigenetics sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Clinical epigenetics
6 skos:broader sg:ontologies/subjects/clinical-genetics
7 skos:definition Clinical epigenetics is the application of molecular biology techniques detecting alterations in DNA methylation or histone modification to diagnose or study disorders characterized by heritable defects in the expression of a gene or genome. Applications include Rett syndrome, disorders of imprinting, uniparental inheritance of chromosomes and chromosome segments, and somatic epigenetic anomalies in cancers.
8 skos:inScheme sg:ontologies/subjects/
9 skos:narrower sg:ontologies/subjects/cancer-epigenetics
10 skos:prefLabel Clinical epigenetics
11 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
12 dcterms:title Nature Subjects Taxonomy
13 sgo:sdDataset onto_subjects
14 rdf:type skos:ConceptScheme
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24 sg:ontologies/subjects/cancer-epigenetics sgo:sdDataset onto_subjects
25 rdf:type npg:Subject
26 skos:Concept
27 rdfs:label Cancer epigenetics
28 skos:broader sg:ontologies/subjects/cancer-genetics
29 sg:ontologies/subjects/clinical-epigenetics
30 skos:definition Cancer epigenetics is the study of somatically heritable changes to molecular processes that influence the flow of information between the DNA of cancer cells and their gene expression patterns. This includes comparative (tumour cell versus normal cell) investigation of nuclear organization, DNA methylation, histone modification and the consequences of genetic mutations in genes encoding epigenetic regulators.
31 skos:inScheme sg:ontologies/subjects/
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33 sg:ontologies/subjects/clinical-genetics sgo:sdDataset onto_subjects
34 rdf:type npg:Subject
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37 skos:broader sg:ontologies/subjects/genetics
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48 skos:Concept sgo:sdDataset for_codes
49 rdf:type rdfs:Class
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52 skos:Concept
 




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