CRISPR-Cas9 genome editing


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

CRISPR-Cas9 genome editing

DESCRIPTION

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be engineered to introduce specific point mutations or insertions.

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HOW TO GET THIS DATA PROGRAMMATICALLY:

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curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/cas9-endonuclease'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/cas9-endonuclease'

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/cas9-endonuclease'


 

This table displays all metadata directly associated to this object as RDF triples.

52 TRIPLES      8 PREDICATES      11 URIs      4 LITERALS

Subject Predicate Object
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6 skos:broader sg:ontologies/subjects/crispr-cas-systems
7 sg:ontologies/subjects/gene-targeting
8 skos:definition CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be engineered to introduce specific point mutations or insertions.
9 skos:inScheme sg:ontologies/subjects/
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11 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
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