Adaptive immunity


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Adaptive immunity

DESCRIPTION

Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly specific to a given antigen and is highly adaptable.

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N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/adaptive-immunity'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/adaptive-immunity'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/adaptive-immunity'


 

This table displays all metadata directly associated to this object as RDF triples.

186 TRIPLES      10 PREDICATES      21 URIs      7 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/adaptive-immunity sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Adaptive immunity
6 skos:altLabel Acquired Immunity
7 Adaptive Immune Response
8 Adoptive Immunity
9 skos:broader sg:ontologies/subjects/immunology
10 sg:ontologies/subjects/immunopathogenesis
11 skos:definition Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly specific to a given antigen and is highly adaptable.
12 skos:inScheme sg:ontologies/subjects/
13 skos:narrower sg:ontologies/subjects/cellular-immunity
14 sg:ontologies/subjects/class-switch-recombination
15 sg:ontologies/subjects/clonal-selection
16 sg:ontologies/subjects/humoral-immunity
17 sg:ontologies/subjects/immune-tolerance
18 sg:ontologies/subjects/somatic-hypermutation
19 sg:ontologies/subjects/vdj-recombination
20 skos:prefLabel Adaptive immunity
21 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
22 dcterms:title Nature Subjects Taxonomy
23 sgo:sdDataset onto_subjects
24 rdf:type skos:ConceptScheme
25 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
26 sg:ontologies/subjects/biological-sciences
27 sg:ontologies/subjects/business-and-commerce
28 sg:ontologies/subjects/earth-and-environmental-sciences
29 sg:ontologies/subjects/health-sciences
30 sg:ontologies/subjects/humanities
31 sg:ontologies/subjects/physical-sciences
32 sg:ontologies/subjects/scientific-community-and-society
33 sg:ontologies/subjects/social-science
34 sg:ontologies/subjects/cellular-immunity sgo:sdDataset onto_subjects
35 rdf:type npg:Subject
36 skos:Concept
37 rdfs:label Cellular immunity
38 skos:altLabel Cell Mediated Immunity
39 Cell-Mediated Immunities
40 Cell-Mediated Immunity
41 Cellular Immune Response
42 Cellular Immune Responses
43 Cellular Immunities
44 skos:broader sg:ontologies/subjects/adaptive-immunity
45 skos:definition Cellular immunity is a protective immune process that involves the activation of phagocytes, antigen-sensitized cytotoxic T cells and the release of cytokines and chemokines in response to antigen. Cellular immunity is most effective against cells infected with viruses, intracellular bacteria, fungi and protozoans, and cancerous cells. It also mediates transplant rejection.
46 skos:inScheme sg:ontologies/subjects/
47 skos:narrower sg:ontologies/subjects/antigen-presentation
48 sg:ontologies/subjects/immunological-memory
49 sg:ontologies/subjects/immunological-surveillance
50 sg:ontologies/subjects/lymphocyte-activation
51 sg:ontologies/subjects/lymphocyte-differentiation
52 skos:prefLabel Cellular immunity
53 sg:ontologies/subjects/class-switch-recombination sgo:sdDataset onto_subjects
54 rdf:type npg:Subject
55 skos:Concept
56 rdfs:label Class switch recombination
57 skos:altLabel Immunoglobulin class switching
58 class switch recombination(CSR)
59 isotype switching
60 isotypic commutation
61 skos:broader sg:ontologies/subjects/adaptive-immunity
62 skos:definition Class switch recombination is a process by which proliferating B cells rearrange the constant region genes in the immunoglobulin heavy chain locus to switch from expressing one class of immunoglobulin (such as IgM) to another (such as IgG). This produces an antibody with different effector properties, without altering its antigen specificity.
63 skos:inScheme sg:ontologies/subjects/
64 skos:prefLabel Class switch recombination
65 sg:ontologies/subjects/clonal-selection sgo:sdDataset onto_subjects
66 rdf:type npg:Subject
67 skos:Concept
68 rdfs:label Clonal selection
69 skos:altLabel clonal selection hypothesis
70 skos:broader sg:ontologies/subjects/adaptive-immunity
71 skos:definition Clonal selection is a process proposed to explain how a single B or T cell that recognizes an antigen that enters the body is selected from the pre-existing cell pool of differing antigen specificities and then reproduced to generate a clonal cell population that eliminates the antigen.
72 skos:inScheme sg:ontologies/subjects/
73 skos:prefLabel Clonal selection
74 sg:ontologies/subjects/humoral-immunity sgo:sdDataset onto_subjects
75 rdf:type npg:Subject
76 skos:Concept
77 rdfs:label Humoral immunity
78 skos:altLabel Humoral Immune Response
79 Humoral Immune Responses
80 skos:broader sg:ontologies/subjects/adaptive-immunity
81 skos:definition Humoral immunity refers to antibody-mediated immune responses. Antibodies are produced by plasma cells and protect the host from infection in three main ways: by binding to pathogens to inhibit their toxic effects or infectivity (neutralization), by coating pathogens and facilitating their uptake and killing by phagocytes (opsonization) and by activating the complement cascade.
82 skos:inScheme sg:ontologies/subjects/
83 skos:narrower sg:ontologies/subjects/antibodies
84 sg:ontologies/subjects/germinal-centres
85 sg:ontologies/subjects/immunological-memory
86 skos:prefLabel Humoral immunity
87 sg:ontologies/subjects/immune-tolerance sgo:sdDataset onto_subjects
88 rdf:type npg:Subject
89 skos:Concept
90 rdfs:label Immune tolerance
91 skos:altLabel Immunological tolerance
92 Immunosuppression
93 Immunosuppression (Physiology)
94 Immunosuppressions
95 Immunosuppressions (Physiology)
96 skos:broader sg:ontologies/subjects/adaptive-immunity
97 skos:definition Immune tolerance is the state of unresponsiveness of the immune system to substances or tissues that have the potential to induce an immune response. Self tolerance to an individual's own antigens is achieved through both central tolerance and peripheral tolerance mechanisms.
98 skos:inScheme sg:ontologies/subjects/
99 skos:narrower sg:ontologies/subjects/central-tolerance
100 sg:ontologies/subjects/peripheral-tolerance
101 skos:prefLabel Immune tolerance
102 sg:ontologies/subjects/immunology sgo:sdDataset onto_subjects
103 rdf:type npg:Subject
104 skos:Concept
105 rdfs:label Immunology
106 skos:altLabel Allergies (Specialty)
107 Allergy (Specialty)
108 Allergy and Immunology
109 Immunology and Allergy
110 skos:broader sg:ontologies/subjects/biological-sciences
111 skos:definition Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms.
112 skos:inScheme sg:ontologies/subjects/
113 skos:narrower sg:ontologies/subjects/adaptive-immunity
114 sg:ontologies/subjects/antigen-processing-and-presentation
115 sg:ontologies/subjects/antimicrobial-responses
116 sg:ontologies/subjects/applied-immunology
117 sg:ontologies/subjects/autoimmunity
118 sg:ontologies/subjects/bone-marrow-transplantation
119 sg:ontologies/subjects/cell-death-and-immune-response
120 sg:ontologies/subjects/chemokines
121 sg:ontologies/subjects/coagulation-system
122 sg:ontologies/subjects/complement-cascade
123 sg:ontologies/subjects/cytokines
124 sg:ontologies/subjects/gene-regulation-in-immune-cells
125 sg:ontologies/subjects/haematopoiesis
126 sg:ontologies/subjects/imaging-the-immune-system
127 sg:ontologies/subjects/immune-cell-death
128 sg:ontologies/subjects/immune-evasion
129 sg:ontologies/subjects/immunogenetics
130 sg:ontologies/subjects/immunological-disorders
131 sg:ontologies/subjects/immunotherapy
132 sg:ontologies/subjects/infection
133 sg:ontologies/subjects/infectious-diseases
134 sg:ontologies/subjects/inflammation
135 sg:ontologies/subjects/innate-immune-cells
136 sg:ontologies/subjects/innate-immunity
137 sg:ontologies/subjects/lymphatic-system
138 sg:ontologies/subjects/lymphocytes
139 sg:ontologies/subjects/lymphoid-tissues
140 sg:ontologies/subjects/mucosal-immunology
141 sg:ontologies/subjects/neuroimmunology
142 sg:ontologies/subjects/osteoimmunology
143 sg:ontologies/subjects/plant-immunology
144 sg:ontologies/subjects/signal-transduction
145 sg:ontologies/subjects/translational-immunology
146 sg:ontologies/subjects/transplant-immunology
147 sg:ontologies/subjects/tumour-immunology
148 sg:ontologies/subjects/vaccines
149 skos:prefLabel Immunology
150 sg:ontologies/subjects/immunopathogenesis sgo:sdDataset onto_subjects
151 rdf:type npg:Subject
152 skos:Concept
153 rdfs:label Immunopathogenesis
154 skos:broader sg:ontologies/subjects/pathogenesis
155 skos:definition Immunopathogenesis is the process of disease development involving an immune response or components thereof.
156 skos:inScheme sg:ontologies/subjects/
157 skos:narrower sg:ontologies/subjects/adaptive-immunity
158 sg:ontologies/subjects/innate-immunity
159 skos:prefLabel Immunopathogenesis
160 sg:ontologies/subjects/somatic-hypermutation sgo:sdDataset onto_subjects
161 rdf:type npg:Subject
162 skos:Concept
163 rdfs:label Somatic hypermutation
164 skos:altLabel Ig Somatic Hypermutation
165 Ig Somatic Hypermutations
166 Immunoglobulin Somatic Hypermutation
167 Immunoglobulin Somatic Hypermutations
168 skos:broader sg:ontologies/subjects/adaptive-immunity
169 skos:definition Somatic hypermutation is a process that allows B cells to mutate the genes that they use to produce antibodies. This enables the B cells to produce antibodies that are better able to bind to bacteria, viruses and other infections.
170 skos:inScheme sg:ontologies/subjects/
171 skos:prefLabel Somatic hypermutation
172 sg:ontologies/subjects/vdj-recombination sgo:sdDataset onto_subjects
173 rdf:type npg:Subject
174 skos:Concept
175 rdfs:label VDJ recombination
176 skos:altLabel V(D)J recombination
177 somatic recombination
178 skos:broader sg:ontologies/subjects/adaptive-immunity
179 skos:definition VDJ recombination is the process by which T cells and B cells randomly assemble different gene segments – known as variable (V), diversity (D) and joining (J) genes – in order to generate unique receptors (known as antigen receptors) that can collectively recognize many different types of molecule.
180 skos:inScheme sg:ontologies/subjects/
181 skos:prefLabel VDJ recombination
182 skos:Concept sgo:sdDataset for_codes
183 rdf:type rdfs:Class
184 rdfs:Resource
185 rdfs:subClassOf rdfs:Resource
186 skos:Concept
 




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