Investigating the detection methods for and incidences of adverse events looked over in daily practice View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2018-2021

FUNDING AMOUNT

17290000.0 JPY

ABSTRACT

This research topic is about iatrogenic adverse events that are becoming known to occur on a daily basis in inpatients and outpatients, and are overlooked without being recognized as iatrogenic during medical treatment. The purpose is to clarify clinical epidemiology such as the frequency and type of events, and to examine their risk factors and preventive / mitigation possibilities. This year, a detailed analysis of the data from the prospective cohort study was carried out, and the analysis database was completed. The following is a summary of the results obtained from the analysis database. A prospective cohort study enrolled 1130 patients (374 in internal medicine, 530 in surgery, 226 in intensive care), with an average age of 70 years and 646 men (57%). From the medical record review, 2977 cases detected as potential adverse events were analyzed, and 1147 iatrogenic adverse events were extracted. Ultimately, 168 (14.6%) adverse events were likely to be missed, 35 (3.1%) were not clear whether they were missed, and 944 (82.3%) were recognized. .. Of the 168 cases, 133 drug-induced adverse events (79.2%), 7 surgery-related adverse events (4.2%), 1 test-related adverse event (0.6%), and 18 medically-judged adverse events (10.7%). There were 1 nursing-related adverse event (0.6%) and 8 management-related adverse events (4.8%). The most overlooked iatrogenic adverse events were central nervous system symptoms such as impaired consciousness (39%), gastrointestinal symptoms (27%), and metabolic / hepatic dysfunction (15%). In terms of severity of iatrogenic adverse events, 9 fatal or life-threatening adverse events (5.4%), 57 serious adverse events (33.9%), and 102 clinically significant adverse events (60.7%). %)Met. This clarified the overall picture of iatrogenic adverse events that are overlooked in daily practice. Through future analysis, it is possible to provide evidence that makes daily medical care safer worldwide. More... »

URL

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H03032

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