Neurological mechanism of aphasia based on mirror neuron system and transcendental localization View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2011-2015

FUNDING AMOUNT

580000 CNY

ABSTRACT

The great discovery of the field of biology and neuroscience - the mirror neuron system (the "observation - implementation" matching system) has been used in recent years to recover from pain syndromes and stroke hemiplegia and achieve significant results. This "brain of the mirror" is the same can bring aphasia to the well-being of patients? There is no answer yet. The preliminary study of the project team found that the mirrored neuron system, which was activated by verbal / manual observation, contained the important language loops of the Broca area, and the observation and execution of speech movements significantly promoted the expression of aphasia. But how does the observation and execution of the combination of hands, as well as hand and speech movements affect the language function of aphasia? What is the brain mechanism? Need to be further clear. Based on the joining and co-design of well-known experts in the field of international mirror neurons, this project integrates classical aphasia assessment method and cognitive neuropsychological evaluation methods to explore the observation and implementation of verbal / manual action on the regulation of five aphasia language functions And to explore the brain mechanism from the brainstem activation, functional junction, fiber junction and nerve metabolism by multi-mode magnetic resonance imaging technique. This study has important theoretical significance and broad application value for mirror neuron system and rehabilitation of aphasia. More... »

URL

http://npd.nsfc.gov.cn/projectDetail.action?pid=81171853

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