Ontology type: schema:MonetaryGrant
2017-2020
FUNDING AMOUNT4680000.0 JPY
ABSTRACTWe measured various autoantibodies in idiopathic interstitial pneumonias and examined their association with clinical findings. In anti-ARS antibody-positive cases, comparison with anti-ARS antibody-positive dermatomyositis-related interstitial pneumonia patients was made. Although the clinical features of both were similar, it was also shown that KL-6 was high and severe in idiopathic interstitial pneumonias cases. The clinical significance of anti-Ro52 antibody was also investigated, and findings suggested that anti-Ro52 antibody-positive patients tended to have a favorable prognosis and were associated with lung involvement.In addition, we found an anti-MDA5 antibody, associated with rapidly progressive interstitial pneumonia in dermatomyositis, in idiopathic interstitial pneumonia. As described above, specific autoantibodies and their lung involvement were also shown in idiopathic interstitial pneumonias. More... »
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