Autoantibodies in idiopathic interstitial pneumonias View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2017-2020

FUNDING AMOUNT

4680000.0 JPY

ABSTRACT

We measured various autoantibodies in idiopathic interstitial pneumonias and examined their association with clinical findings. In anti-ARS antibody-positive cases, comparison with anti-ARS antibody-positive dermatomyositis-related interstitial pneumonia patients was made. Although the clinical features of both were similar, it was also shown that KL-6 was high and severe in idiopathic interstitial pneumonias cases. The clinical significance of anti-Ro52 antibody was also investigated, and findings suggested that anti-Ro52 antibody-positive patients tended to have a favorable prognosis and were associated with lung involvement.In addition, we found an anti-MDA5 antibody, associated with rapidly progressive interstitial pneumonia in dermatomyositis, in idiopathic interstitial pneumonia. As described above, specific autoantibodies and their lung involvement were also shown in idiopathic interstitial pneumonias. More... »

URL

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K09617

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