Reconstruction of the mechanisms of human evolution on the territory of Central and Northern Eurasia in the late Pleistocene-Early Holocene ... View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2013-2013

FUNDING AMOUNT

N/A

ABSTRACT

In the light of modern ideas about the different stages of anthropogenesis, one of the most interesting and promising regions for study is Central Eurasia and the adjacent regions of Northern Eurasia. It is for this region that the coexistence of different species of late hominids that contributed to the early stages of the formation of the features of the gene pool of the anatomically modern population - Neanderthals, Denisians - is shown. The data of both ethnogenomics and physical anthropology show that it was in the designated region during the late Pleistocene-Early Holocene that large groups of population were forming, showing a specific character in relation to the population of other territories of Eurasia, both from the point of view of the structure of the gene pool and from the craniometric And odontological criteria. Complex multidisciplinary approaches based on the use of modern paleogenetic and bioinformatic methods play an important role in the study of these processes. Their use makes it possible to investigate questions that are inaccessible to study by narrowly specialized approaches. This project is aimed at the reconstruction by complex methods of paleogeneomics and bioinformatics of the mechanisms of human evolution in the territory of Central and Northern Eurasia in the late Pleistocene - early Holocene. The implementation of the experimental part of the project is based on the use of methods of paleogenetics, high-performance sequencing of ancient DNA, which allows obtaining data on the structure of DNA from the remains of representatives of the ancient population, up to several tens of thousands of years. Bioinformatics methods will be used to analyze these data, the results of which will allow reconstructing the formation of the population's genetic makeup in the early Holocene, assessing the contribution of late hominids to the gene pool of the anatomically modern population of Eurasia, identifying molecular genetic mechanisms ensuring the adaptation of populations to the conditions of different regions of Eurasia and assessing the effects of mutations , Fixed during the evolution of the genus Homo on the formation of the phenotype of ancient people and modern man. More... »

URL

http://www.rfbr.ru/rffi/ru/project_search/o_1910210

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