Melanocyte stem cells as a niche for corneal epithelial stem cells View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2013-2015

FUNDING AMOUNT

4160000 JPY

ABSTRACT

Based on the localization of melanocytes in primary human limbal epithelial cell sheets, we hypothesized that melanocytes or melanocyte stem cells act as a limbal epithelial stem cell niche, even in vitro. However, our results suggested that although melanocytes in vitro supplied melanosome to the epithelial cells, melanocytes seemed to not have the additional effects on epithelial stem cells in vitro. Rather, limbal epithelial stem/progenitor cells seemed to maintain melanocytes in vitro. We intend to report our data including melanocyte localization in epithelial sheets by paper. More... »

URL

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25861650

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