Preparation of Smart Biomaterials Using Dynamic Crosslinks and Their Biomedical Applications View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2012-2016

FUNDING AMOUNT

18200000 JPY

ABSTRACT

In this study, biomolecularly stimuli-responsive gels, particles and films with molecular complexes as dynamic crosslinks were strategically designed as smart biomaterials for constructing novel medical systems. The hydrogels, particles and films underwent changes in the volume in response to a target biomolecule. We developed self-regulated drug delivery systems (DDS) and diagnostic sensors using the biomolecularly stimuli-responsive gels, particles and films. In addition, photo-responsive polymers with micro-patternable surfaces were synthesized using photo-dimerization moieties as dynamic crosslinks. Photo-irradiation to the photo-responsive polymers through photo-masks resulted in the formation of micropatterns. The micropatterned surfaces were applied to microcontact printing and cell cultures. More... »

URL

https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24300175

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2210", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2209", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2203", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2203", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2209", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "amount": {
      "currency": "JPY", 
      "type": "MonetaryAmount", 
      "value": "18200000"
    }, 
    "description": "In this study, biomolecularly stimuli-responsive gels, particles and films with molecular complexes as dynamic crosslinks were strategically designed as smart biomaterials for constructing novel medical systems. The hydrogels, particles and films underwent changes in the volume in response to a target biomolecule. We developed self-regulated drug delivery systems (DDS) and diagnostic sensors using the biomolecularly stimuli-responsive gels, particles and films. In addition, photo-responsive polymers with micro-patternable surfaces were synthesized using photo-dimerization moieties as dynamic crosslinks. Photo-irradiation to the photo-responsive polymers through photo-masks resulted in the formation of micropatterns. The micropatterned surfaces were applied to microcontact printing and cell cultures.", 
    "endDate": "2016-03-31T00:00:00Z", 
    "funder": {
      "id": "https://www.grid.ac/institutes/grid.54432.34", 
      "type": "Organization"
    }, 
    "id": "sg:grant.6084732", 
    "identifier": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "6084732"
        ]
      }, 
      {
        "name": "kaken_id", 
        "type": "PropertyValue", 
        "value": [
          "24300175"
        ]
      }
    ], 
    "inLanguage": [
      "en"
    ], 
    "keywords": [
      "dynamic crosslinks", 
      "micropatterned surfaces", 
      "cell culture", 
      "molecular complexes", 
      "micropatterns", 
      "photo-dimerization moieties", 
      "preparation", 
      "films", 
      "Dynamic Crosslinks", 
      "photo-mask", 
      "hydrogels", 
      "drug delivery systems", 
      "micro-patternable surfaces", 
      "changes", 
      "novel", 
      "Biomedical Applications", 
      "target biomolecules", 
      "formation", 
      "biomolecularly stimuli-responsive gels", 
      "Smart Biomaterials", 
      "self", 
      "diagnostic sensors", 
      "response", 
      "photo-irradiation", 
      "photo-responsive polymers", 
      "particles", 
      "medical system", 
      "printing", 
      "volume", 
      "addition", 
      "smart biomaterials", 
      "study"
    ], 
    "name": "Preparation of Smart Biomaterials Using Dynamic Crosslinks and Their Biomedical Applications", 
    "recipient": [
      {
        "id": "https://www.grid.ac/institutes/grid.412013.5", 
        "type": "Organization"
      }
    ], 
    "sameAs": [
      "https://app.dimensions.ai/details/grant/grant.6084732"
    ], 
    "sdDataset": "grants", 
    "sdDatePublished": "2019-03-07T11:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com.uberresearch.data.processor/core_data/20181219_192338/projects/base/kaken_projects_29.xml.gz", 
    "startDate": "2012-04-01T00:00:00Z", 
    "type": "MonetaryGrant", 
    "url": "https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24300175"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/grant.6084732'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/grant.6084732'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/grant.6084732'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/grant.6084732'


 

This table displays all metadata directly associated to this object as RDF triples.

72 TRIPLES      19 PREDICATES      54 URIs      45 LITERALS      4 BLANK NODES

Subject Predicate Object
1 sg:grant.6084732 schema:about anzsrc-for:2203
2 anzsrc-for:2209
3 anzsrc-for:2210
4 schema:amount Ne7cedb5449774931877750b7942b1601
5 schema:description In this study, biomolecularly stimuli-responsive gels, particles and films with molecular complexes as dynamic crosslinks were strategically designed as smart biomaterials for constructing novel medical systems. The hydrogels, particles and films underwent changes in the volume in response to a target biomolecule. We developed self-regulated drug delivery systems (DDS) and diagnostic sensors using the biomolecularly stimuli-responsive gels, particles and films. In addition, photo-responsive polymers with micro-patternable surfaces were synthesized using photo-dimerization moieties as dynamic crosslinks. Photo-irradiation to the photo-responsive polymers through photo-masks resulted in the formation of micropatterns. The micropatterned surfaces were applied to microcontact printing and cell cultures.
6 schema:endDate 2016-03-31T00:00:00Z
7 schema:funder https://www.grid.ac/institutes/grid.54432.34
8 schema:identifier Na051f23e3f844869b84c7b2368504d22
9 Nf13c2fc89cb24284a865e76c87c7fdf9
10 schema:inLanguage en
11 schema:keywords Biomedical Applications
12 Dynamic Crosslinks
13 Smart Biomaterials
14 addition
15 biomolecularly stimuli-responsive gels
16 cell culture
17 changes
18 diagnostic sensors
19 drug delivery systems
20 dynamic crosslinks
21 films
22 formation
23 hydrogels
24 medical system
25 micro-patternable surfaces
26 micropatterned surfaces
27 micropatterns
28 molecular complexes
29 novel
30 particles
31 photo-dimerization moieties
32 photo-irradiation
33 photo-mask
34 photo-responsive polymers
35 preparation
36 printing
37 response
38 self
39 smart biomaterials
40 study
41 target biomolecules
42 volume
43 schema:name Preparation of Smart Biomaterials Using Dynamic Crosslinks and Their Biomedical Applications
44 schema:recipient https://www.grid.ac/institutes/grid.412013.5
45 schema:sameAs https://app.dimensions.ai/details/grant/grant.6084732
46 schema:sdDatePublished 2019-03-07T11:47
47 schema:sdLicense https://scigraph.springernature.com/explorer/license/
48 schema:sdPublisher N2b0d6fc22a224169b38492611e0b3d91
49 schema:startDate 2012-04-01T00:00:00Z
50 schema:url https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24300175
51 sgo:license sg:explorer/license/
52 sgo:sdDataset grants
53 rdf:type schema:MonetaryGrant
54 N2b0d6fc22a224169b38492611e0b3d91 schema:name Springer Nature - SN SciGraph project
55 rdf:type schema:Organization
56 Na051f23e3f844869b84c7b2368504d22 schema:name dimensions_id
57 schema:value 6084732
58 rdf:type schema:PropertyValue
59 Ne7cedb5449774931877750b7942b1601 schema:currency JPY
60 schema:value 18200000
61 rdf:type schema:MonetaryAmount
62 Nf13c2fc89cb24284a865e76c87c7fdf9 schema:name kaken_id
63 schema:value 24300175
64 rdf:type schema:PropertyValue
65 anzsrc-for:2203 schema:inDefinedTermSet anzsrc-for:
66 rdf:type schema:DefinedTerm
67 anzsrc-for:2209 schema:inDefinedTermSet anzsrc-for:
68 rdf:type schema:DefinedTerm
69 anzsrc-for:2210 schema:inDefinedTermSet anzsrc-for:
70 rdf:type schema:DefinedTerm
71 https://www.grid.ac/institutes/grid.412013.5 schema:Organization
72 https://www.grid.ac/institutes/grid.54432.34 schema:Organization
 




Preview window. Press ESC to close (or click here)


...