Molecular Mechanism of abnormally high blood sugar hormones and stress protein gene regulation caused by cadmium metabolism of sugar and ... View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

2012-2013

FUNDING AMOUNT

150000 CNY

ABSTRACT

Material and energy metabolism is one of the basic characteristics of the organism. The project on the basis of seven National Natural Science Foundation, under the premise of the early research accumulation, utilization and transmission electron microscopy confocal immunocytochemistry and ELISA, two-dimensional electrophoresis and mass spectrometry, cloning, and other real-time quantitative PCR way to crabs were studied cadmium effects on glucose metabolism pathway five key enzyme activity and hyperglycemic hormone gene expression and regulation of glucose metabolism in the molecular mechanism of cell; metabolic activity of the protein and amino acid content and heat shock protein HSP70, radical Clear protein SOD, GST gene molecular protection mechanisms; fat metabolism in fat digestion, transport and synthesis of important activity; ATP energy demand mRNA expression and hemocyanin, CCO-1 gene transcription and mitochondrial membrane potential. Through research, clarify cadmium hyperglycemia hormone synthesis and secretion mechanism and cause interference or suppression of protein synthesis and amino acid metabolism of the major defense mechanism in the fat composition, and its biochemical mechanism of functioning of the reserve, mitochondrial function and to hemocyanin regulatory mechanism of oxygen utilization. Strong and easy screening sensitivity detection of biological effector molecules, improve biological assessment methods, provide a scientific basis for the health of aquatic farming. More... »

URL

http://npd.nsfc.gov.cn/projectDetail.action?pid=31272319

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2206", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "amount": {
      "currency": "CNY", 
      "type": "MonetaryAmount", 
      "value": "150000"
    }, 
    "description": "Material and energy metabolism is one of the basic characteristics of the organism. The project on the basis of seven National Natural Science Foundation, under the premise of the early research accumulation, utilization and transmission electron microscopy confocal immunocytochemistry and ELISA, two-dimensional electrophoresis and mass spectrometry, cloning, and other real-time quantitative PCR way to crabs were studied cadmium effects on glucose metabolism pathway five key enzyme activity and hyperglycemic hormone gene expression and regulation of glucose metabolism in the molecular mechanism of cell; metabolic activity of the protein and amino acid content and heat shock protein HSP70, radical Clear protein SOD, GST gene molecular protection mechanisms; fat metabolism in fat digestion, transport and synthesis of important activity; ATP energy demand mRNA expression and hemocyanin, CCO-1 gene transcription and mitochondrial membrane potential. Through research, clarify cadmium hyperglycemia hormone synthesis and secretion mechanism and cause interference or suppression of protein synthesis and amino acid metabolism of the major defense mechanism in the fat composition, and its biochemical mechanism of functioning of the reserve, mitochondrial function and to hemocyanin regulatory mechanism of oxygen utilization. Strong and easy screening sensitivity detection of biological effector molecules, improve biological assessment methods, provide a scientific basis for the health of aquatic farming.", 
    "endDate": "2013-12-30T00:00:00Z", 
    "funder": {
      "id": "https://www.grid.ac/institutes/grid.419696.5", 
      "type": "Organization"
    }, 
    "id": "sg:grant.5016379", 
    "identifier": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "5016379"
        ]
      }, 
      {
        "name": "nsfc_id", 
        "type": "PropertyValue", 
        "value": [
          "31272319"
        ]
      }
    ], 
    "inLanguage": [
      "zh"
    ], 
    "keywords": [
      "hemocyanin", 
      "regulatory mechanisms", 
      "functioning", 
      "metabolic activity", 
      "mass spectrometry", 
      "fat digestion", 
      "early research accumulation", 
      "glucose metabolism", 
      "transmission electron microscopy", 
      "scientific basis", 
      "ATP energy demand mRNA expression", 
      "sugar", 
      "molecular protection mechanisms", 
      "mitochondrial function", 
      "cadmium effects", 
      "CCO-1 gene transcription", 
      "cloning", 
      "protein synthesis", 
      "cells", 
      "GST genes", 
      "transport", 
      "oxygen utilization", 
      "hyperglycemic hormone gene expression", 
      "biological effector molecules", 
      "aquatic farming", 
      "biological assessment methods", 
      "National Natural Science Foundation", 
      "amino acid metabolism", 
      "protein crabs", 
      "easy screening sensitivity detection", 
      "basis", 
      "amino acid content", 
      "stress protein gene regulation", 
      "energy metabolism", 
      "synthesis", 
      "reserves", 
      "regulation", 
      "high blood sugar hormones", 
      "ELISA", 
      "mitochondrial membrane potential", 
      "premise", 
      "radical Clear protein SOD", 
      "crabs", 
      "fat metabolism", 
      "utilization", 
      "other real-time quantitative PCR way", 
      "heat shock protein HSP70", 
      "fat composition", 
      "cadmium hyperglycemia hormone synthesis", 
      "health", 
      "interference", 
      "glucose metabolism pathway five key enzyme activity", 
      "biochemical mechanisms", 
      "protein", 
      "cadmium metabolism", 
      "secretion mechanism", 
      "basic characteristics", 
      "research", 
      "molecular mechanisms", 
      "confocal immunocytochemistry", 
      "major defense mechanism", 
      "project", 
      "important activity", 
      "two-dimensional electrophoresis", 
      "suppression", 
      "organisms"
    ], 
    "name": "Molecular Mechanism of abnormally high blood sugar hormones and stress protein gene regulation caused by cadmium metabolism of sugar and protein crabs", 
    "recipient": [
      {
        "id": "https://www.grid.ac/institutes/grid.163032.5", 
        "type": "Organization"
      }, 
      {
        "affiliation": {
          "id": "https://www.grid.ac/institutes/grid.163032.5", 
          "name": "Shanxi University", 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Lan", 
        "id": "sg:person.0712247506.17", 
        "type": "Person"
      }, 
      {
        "member": "sg:person.0712247506.17", 
        "roleName": "PI", 
        "type": "Role"
      }
    ], 
    "sameAs": [
      "https://app.dimensions.ai/details/grant/grant.5016379"
    ], 
    "sdDataset": "grants", 
    "sdDatePublished": "2019-03-07T12:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com.uberresearch.data.processor/core_data/20181219_192338/projects/base/nsfc_projects_0.xml.gz", 
    "startDate": "2012-12-31T00:00:00Z", 
    "type": "MonetaryGrant", 
    "url": "http://npd.nsfc.gov.cn/projectDetail.action?pid=31272319"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/grant.5016379'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/grant.5016379'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/grant.5016379'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/grant.5016379'


 

This table displays all metadata directly associated to this object as RDF triples.

110 TRIPLES      19 PREDICATES      88 URIs      80 LITERALS      5 BLANK NODES

Subject Predicate Object
1 sg:grant.5016379 schema:about anzsrc-for:2206
2 schema:amount N5cd5967cb0f34fda9b848f6a018ea8e5
3 schema:description Material and energy metabolism is one of the basic characteristics of the organism. The project on the basis of seven National Natural Science Foundation, under the premise of the early research accumulation, utilization and transmission electron microscopy confocal immunocytochemistry and ELISA, two-dimensional electrophoresis and mass spectrometry, cloning, and other real-time quantitative PCR way to crabs were studied cadmium effects on glucose metabolism pathway five key enzyme activity and hyperglycemic hormone gene expression and regulation of glucose metabolism in the molecular mechanism of cell; metabolic activity of the protein and amino acid content and heat shock protein HSP70, radical Clear protein SOD, GST gene molecular protection mechanisms; fat metabolism in fat digestion, transport and synthesis of important activity; ATP energy demand mRNA expression and hemocyanin, CCO-1 gene transcription and mitochondrial membrane potential. Through research, clarify cadmium hyperglycemia hormone synthesis and secretion mechanism and cause interference or suppression of protein synthesis and amino acid metabolism of the major defense mechanism in the fat composition, and its biochemical mechanism of functioning of the reserve, mitochondrial function and to hemocyanin regulatory mechanism of oxygen utilization. Strong and easy screening sensitivity detection of biological effector molecules, improve biological assessment methods, provide a scientific basis for the health of aquatic farming.
4 schema:endDate 2013-12-30T00:00:00Z
5 schema:funder https://www.grid.ac/institutes/grid.419696.5
6 schema:identifier N6517081cf22b48b5bcb50cd96e3192ce
7 Nea4e8b1920fa41919775316c296d6a7d
8 schema:inLanguage zh
9 schema:keywords ATP energy demand mRNA expression
10 CCO-1 gene transcription
11 ELISA
12 GST genes
13 National Natural Science Foundation
14 amino acid content
15 amino acid metabolism
16 aquatic farming
17 basic characteristics
18 basis
19 biochemical mechanisms
20 biological assessment methods
21 biological effector molecules
22 cadmium effects
23 cadmium hyperglycemia hormone synthesis
24 cadmium metabolism
25 cells
26 cloning
27 confocal immunocytochemistry
28 crabs
29 early research accumulation
30 easy screening sensitivity detection
31 energy metabolism
32 fat composition
33 fat digestion
34 fat metabolism
35 functioning
36 glucose metabolism
37 glucose metabolism pathway five key enzyme activity
38 health
39 heat shock protein HSP70
40 hemocyanin
41 high blood sugar hormones
42 hyperglycemic hormone gene expression
43 important activity
44 interference
45 major defense mechanism
46 mass spectrometry
47 metabolic activity
48 mitochondrial function
49 mitochondrial membrane potential
50 molecular mechanisms
51 molecular protection mechanisms
52 organisms
53 other real-time quantitative PCR way
54 oxygen utilization
55 premise
56 project
57 protein
58 protein crabs
59 protein synthesis
60 radical Clear protein SOD
61 regulation
62 regulatory mechanisms
63 research
64 reserves
65 scientific basis
66 secretion mechanism
67 stress protein gene regulation
68 sugar
69 suppression
70 synthesis
71 transmission electron microscopy
72 transport
73 two-dimensional electrophoresis
74 utilization
75 schema:name Molecular Mechanism of abnormally high blood sugar hormones and stress protein gene regulation caused by cadmium metabolism of sugar and protein crabs
76 schema:recipient Nc58986a8f1694a98a0d6e608c3aaadaf
77 sg:person.0712247506.17
78 https://www.grid.ac/institutes/grid.163032.5
79 schema:sameAs https://app.dimensions.ai/details/grant/grant.5016379
80 schema:sdDatePublished 2019-03-07T12:39
81 schema:sdLicense https://scigraph.springernature.com/explorer/license/
82 schema:sdPublisher Ne49534e87a9f414bbf51c6a6c45386e6
83 schema:startDate 2012-12-31T00:00:00Z
84 schema:url http://npd.nsfc.gov.cn/projectDetail.action?pid=31272319
85 sgo:license sg:explorer/license/
86 sgo:sdDataset grants
87 rdf:type schema:MonetaryGrant
88 N5cd5967cb0f34fda9b848f6a018ea8e5 schema:currency CNY
89 schema:value 150000
90 rdf:type schema:MonetaryAmount
91 N6517081cf22b48b5bcb50cd96e3192ce schema:name dimensions_id
92 schema:value 5016379
93 rdf:type schema:PropertyValue
94 Nc58986a8f1694a98a0d6e608c3aaadaf schema:member sg:person.0712247506.17
95 schema:roleName PI
96 rdf:type schema:Role
97 Ne49534e87a9f414bbf51c6a6c45386e6 schema:name Springer Nature - SN SciGraph project
98 rdf:type schema:Organization
99 Nea4e8b1920fa41919775316c296d6a7d schema:name nsfc_id
100 schema:value 31272319
101 rdf:type schema:PropertyValue
102 anzsrc-for:2206 schema:inDefinedTermSet anzsrc-for:
103 rdf:type schema:DefinedTerm
104 sg:person.0712247506.17 schema:affiliation https://www.grid.ac/institutes/grid.163032.5
105 schema:familyName Wang
106 schema:givenName Lan
107 rdf:type schema:Person
108 https://www.grid.ac/institutes/grid.163032.5 schema:name Shanxi University
109 rdf:type schema:Organization
110 https://www.grid.ac/institutes/grid.419696.5 schema:Organization
 




Preview window. Press ESC to close (or click here)


...