Neurolinguistic Investigations of Aphasia and Recovery View Homepage


Ontology type: schema:MonetaryGrant     


Grant Info

YEARS

1992-2021

FUNDING AMOUNT

6193279 USD

ABSTRACT

Project Summary The overarching goal of this project is to develop effective language treatment protocols for individuals with stroke-induced agrammatic aphasia. Building on theories of linguistic representation and the neurocognitive mechanisms of sentence processing in healthy speakers, this project investigates the processes that support sentence production and comprehension (and treatment-induced recovery) in agrammatic aphasia, using a series of online processing experiments as well as an experimental treatment study. This project uses primarily online methods to examine thematic integration processes in sentence production and comprehension. Thematic integration is the incremental mapping between thematic roles (e.g., Agent, Theme) and sentence constituents (e.g., subject, object) ? i.e., the processes of comprehending or expressing ?who did what to whom.? These processes are essential for successful sentence production and comprehension but appear to be impaired in agrammatic aphasia. A series of four sentence comprehension experiments, using eyetracking and ERP, test the hypothesis that impaired thematic prediction contributes to impairments in thematic role assignment and sentence comprehension accuracy. Four sentence production experiments, using eyetracking and priming paradigms, examine the effects of impaired thematic planning processes on sentence production ability. Studies also examine the relation between comprehension and production abilities, testing the hypothesis that thematic integration deficits are seen across domains in agrammatic aphasia. Further, an experimental treatment study compares the effectiveness of two novel extensions of Treatment of Underlying Forms (TUF; Thompson & Shapiro, 2005), which train thematic integration using a TUF-Structural approach, which emphasizes verb-based structural processing and a TUF- Word approach, focused on word-by-word incremental processing. Consistent with previous work, both versions of TUF are expected to support improved sentence production, including generalization to simpler linguistically-related structures; however, TUF-Word is expected to foster stronger gains in comprehension, due to its emphasis on training incremental (word-by-word) thematic processing. In addition, this project investigates the neurocognitive mechanisms of treatment-induced language recovery using eyetracking and sentence production paradigms, as well as the effects of language treatment on functional communication ability. The results of this work will contribute to the understanding of sentence processing in aphasia and in healthy adults, the factors that contribute to effective treatment for sentence-level impairments, as well as the neurocognitive mechanisms of treatment-induced recovery in agrammatic aphasia. More... »

URL

http://projectreporter.nih.gov/project_info_description.cfm?aid=9405535

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2217", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2217", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "amount": {
      "currency": "USD", 
      "type": "MonetaryAmount", 
      "value": "6193279"
    }, 
    "description": "Project Summary The overarching goal of this project is to develop effective language treatment protocols for individuals with stroke-induced agrammatic aphasia. Building on theories of linguistic representation and the neurocognitive mechanisms of sentence processing in healthy speakers, this project investigates the processes that support sentence production and comprehension (and treatment-induced recovery) in agrammatic aphasia, using a series of online processing experiments as well as an experimental treatment study. This project uses primarily online methods to examine thematic integration processes in sentence production and comprehension. Thematic integration is the incremental mapping between thematic roles (e.g., Agent, Theme) and sentence constituents (e.g., subject, object) ? i.e., the processes of comprehending or expressing ?who did what to whom.? These processes are essential for successful sentence production and comprehension but appear to be impaired in agrammatic aphasia. A series of four sentence comprehension experiments, using eyetracking and ERP, test the hypothesis that impaired thematic prediction contributes to impairments in thematic role assignment and sentence comprehension accuracy. Four sentence production experiments, using eyetracking and priming paradigms, examine the effects of impaired thematic planning processes on sentence production ability. Studies also examine the relation between comprehension and production abilities, testing the hypothesis that thematic integration deficits are seen across domains in agrammatic aphasia. Further, an experimental treatment study compares the effectiveness of two novel extensions of Treatment of Underlying Forms (TUF; Thompson & Shapiro, 2005), which train thematic integration using a TUF-Structural approach, which emphasizes verb-based structural processing and a TUF- Word approach, focused on word-by-word incremental processing. Consistent with previous work, both versions of TUF are expected to support improved sentence production, including generalization to simpler linguistically-related structures; however, TUF-Word is expected to foster stronger gains in comprehension, due to its emphasis on training incremental (word-by-word) thematic processing. In addition, this project investigates the neurocognitive mechanisms of treatment-induced language recovery using eyetracking and sentence production paradigms, as well as the effects of language treatment on functional communication ability. The results of this work will contribute to the understanding of sentence processing in aphasia and in healthy adults, the factors that contribute to effective treatment for sentence-level impairments, as well as the neurocognitive mechanisms of treatment-induced recovery in agrammatic aphasia.", 
    "endDate": "2021-12-31T00:00:00Z", 
    "funder": {
      "id": "https://www.grid.ac/institutes/grid.214431.1", 
      "type": "Organization"
    }, 
    "id": "sg:grant.2488038", 
    "identifier": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "2488038"
        ]
      }, 
      {
        "name": "nih_id", 
        "type": "PropertyValue", 
        "value": [
          "R01DC001948"
        ]
      }
    ], 
    "inLanguage": [
      "en"
    ], 
    "keywords": [
      "online method", 
      "work", 
      "Neurolinguistic Investigations", 
      "individuals", 
      "sentence-level impairments", 
      "thematic processing", 
      "ERP", 
      "Underlying Forms", 
      "production ability", 
      "neurocognitive mechanisms", 
      "structural processing", 
      "linguistic representation", 
      "themes", 
      "generalization", 
      "series", 
      "thematic planning processes", 
      "thematic integration deficits", 
      "sentence production paradigms", 
      "effect", 
      "thematic integration processes", 
      "novel extension", 
      "project summaries", 
      "aphasia", 
      "thematic role assignment", 
      "sentence production abilities", 
      "paradigms", 
      "online processing experiments", 
      "words", 
      "version", 
      "incremental processing", 
      "impairment", 
      "improved sentence production", 
      "understanding", 
      "hypothesis", 
      "process", 
      "language treatment", 
      "TUF-Structural approach", 
      "incremental mapping", 
      "factors", 
      "effective treatment", 
      "sentence comprehension experiments", 
      "domain", 
      "verb", 
      "TUF- Word approach", 
      "results", 
      "theory", 
      "eyetracking", 
      "healthy speakers", 
      "comprehension", 
      "sentence processing", 
      "object", 
      "successful sentence production", 
      "healthy adults", 
      "functional communication abilities", 
      "project", 
      "emphasis", 
      "tuf", 
      "study", 
      "sentence comprehension accuracy", 
      "effective language treatment protocols", 
      "agrammatic aphasia", 
      "sentence production", 
      "structure", 
      "sentence constituents", 
      "recovery", 
      "TUF-Word", 
      "sentence production experiments", 
      "language recovery", 
      "strong gain", 
      "addition", 
      "stroke", 
      "experimental treatment study", 
      "Thompson & Shapiro", 
      "thematic prediction", 
      "agents", 
      "treatment", 
      "previous work", 
      "relation", 
      "overarching goal", 
      "thematic integration", 
      "thematic roles", 
      "effectiveness"
    ], 
    "name": "Neurolinguistic Investigations of Aphasia and Recovery", 
    "recipient": [
      {
        "id": "https://www.grid.ac/institutes/grid.16753.36", 
        "type": "Organization"
      }, 
      {
        "affiliation": {
          "id": "https://www.grid.ac/institutes/grid.16753.36", 
          "name": "NORTHWESTERN UNIVERSITY", 
          "type": "Organization"
        }, 
        "familyName": "THOMPSON", 
        "givenName": "CYNTHIA K", 
        "id": "sg:person.0762422112.05", 
        "type": "Person"
      }, 
      {
        "member": "sg:person.0762422112.05", 
        "roleName": "PI", 
        "type": "Role"
      }
    ], 
    "sameAs": [
      "https://app.dimensions.ai/details/grant/grant.2488038"
    ], 
    "sdDataset": "grants", 
    "sdDatePublished": "2019-03-07T12:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com.uberresearch.data.processor/core_data/20181219_192338/projects/base/nih_projects_7.xml.gz", 
    "startDate": "1992-09-01T00:00:00Z", 
    "type": "MonetaryGrant", 
    "url": "http://projectreporter.nih.gov/project_info_description.cfm?aid=9405535"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/grant.2488038'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/grant.2488038'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/grant.2488038'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/grant.2488038'


 

This table displays all metadata directly associated to this object as RDF triples.

126 TRIPLES      19 PREDICATES      104 URIs      96 LITERALS      5 BLANK NODES

Subject Predicate Object
1 sg:grant.2488038 schema:about anzsrc-for:2217
2 schema:amount N65256e2a13864a61bfaf15b3926d900f
3 schema:description Project Summary The overarching goal of this project is to develop effective language treatment protocols for individuals with stroke-induced agrammatic aphasia. Building on theories of linguistic representation and the neurocognitive mechanisms of sentence processing in healthy speakers, this project investigates the processes that support sentence production and comprehension (and treatment-induced recovery) in agrammatic aphasia, using a series of online processing experiments as well as an experimental treatment study. This project uses primarily online methods to examine thematic integration processes in sentence production and comprehension. Thematic integration is the incremental mapping between thematic roles (e.g., Agent, Theme) and sentence constituents (e.g., subject, object) ? i.e., the processes of comprehending or expressing ?who did what to whom.? These processes are essential for successful sentence production and comprehension but appear to be impaired in agrammatic aphasia. A series of four sentence comprehension experiments, using eyetracking and ERP, test the hypothesis that impaired thematic prediction contributes to impairments in thematic role assignment and sentence comprehension accuracy. Four sentence production experiments, using eyetracking and priming paradigms, examine the effects of impaired thematic planning processes on sentence production ability. Studies also examine the relation between comprehension and production abilities, testing the hypothesis that thematic integration deficits are seen across domains in agrammatic aphasia. Further, an experimental treatment study compares the effectiveness of two novel extensions of Treatment of Underlying Forms (TUF; Thompson & Shapiro, 2005), which train thematic integration using a TUF-Structural approach, which emphasizes verb-based structural processing and a TUF- Word approach, focused on word-by-word incremental processing. Consistent with previous work, both versions of TUF are expected to support improved sentence production, including generalization to simpler linguistically-related structures; however, TUF-Word is expected to foster stronger gains in comprehension, due to its emphasis on training incremental (word-by-word) thematic processing. In addition, this project investigates the neurocognitive mechanisms of treatment-induced language recovery using eyetracking and sentence production paradigms, as well as the effects of language treatment on functional communication ability. The results of this work will contribute to the understanding of sentence processing in aphasia and in healthy adults, the factors that contribute to effective treatment for sentence-level impairments, as well as the neurocognitive mechanisms of treatment-induced recovery in agrammatic aphasia.
4 schema:endDate 2021-12-31T00:00:00Z
5 schema:funder https://www.grid.ac/institutes/grid.214431.1
6 schema:identifier N00c699e0af0e429c9b2b6b660eea537e
7 Na4e889c35ca9487d89b15f1deceef29d
8 schema:inLanguage en
9 schema:keywords ERP
10 Neurolinguistic Investigations
11 TUF- Word approach
12 TUF-Structural approach
13 TUF-Word
14 Thompson & Shapiro
15 Underlying Forms
16 addition
17 agents
18 agrammatic aphasia
19 aphasia
20 comprehension
21 domain
22 effect
23 effective language treatment protocols
24 effective treatment
25 effectiveness
26 emphasis
27 experimental treatment study
28 eyetracking
29 factors
30 functional communication abilities
31 generalization
32 healthy adults
33 healthy speakers
34 hypothesis
35 impairment
36 improved sentence production
37 incremental mapping
38 incremental processing
39 individuals
40 language recovery
41 language treatment
42 linguistic representation
43 neurocognitive mechanisms
44 novel extension
45 object
46 online method
47 online processing experiments
48 overarching goal
49 paradigms
50 previous work
51 process
52 production ability
53 project
54 project summaries
55 recovery
56 relation
57 results
58 sentence comprehension accuracy
59 sentence comprehension experiments
60 sentence constituents
61 sentence processing
62 sentence production
63 sentence production abilities
64 sentence production experiments
65 sentence production paradigms
66 sentence-level impairments
67 series
68 stroke
69 strong gain
70 structural processing
71 structure
72 study
73 successful sentence production
74 thematic integration
75 thematic integration deficits
76 thematic integration processes
77 thematic planning processes
78 thematic prediction
79 thematic processing
80 thematic role assignment
81 thematic roles
82 themes
83 theory
84 treatment
85 tuf
86 understanding
87 verb
88 version
89 words
90 work
91 schema:name Neurolinguistic Investigations of Aphasia and Recovery
92 schema:recipient N17ca66b773864fc592afef63a4051b34
93 sg:person.0762422112.05
94 https://www.grid.ac/institutes/grid.16753.36
95 schema:sameAs https://app.dimensions.ai/details/grant/grant.2488038
96 schema:sdDatePublished 2019-03-07T12:15
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N31503ce75f9e4125af8a986efd90fd2c
99 schema:startDate 1992-09-01T00:00:00Z
100 schema:url http://projectreporter.nih.gov/project_info_description.cfm?aid=9405535
101 sgo:license sg:explorer/license/
102 sgo:sdDataset grants
103 rdf:type schema:MonetaryGrant
104 N00c699e0af0e429c9b2b6b660eea537e schema:name dimensions_id
105 schema:value 2488038
106 rdf:type schema:PropertyValue
107 N17ca66b773864fc592afef63a4051b34 schema:member sg:person.0762422112.05
108 schema:roleName PI
109 rdf:type schema:Role
110 N31503ce75f9e4125af8a986efd90fd2c schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 N65256e2a13864a61bfaf15b3926d900f schema:currency USD
113 schema:value 6193279
114 rdf:type schema:MonetaryAmount
115 Na4e889c35ca9487d89b15f1deceef29d schema:name nih_id
116 schema:value R01DC001948
117 rdf:type schema:PropertyValue
118 anzsrc-for:2217 schema:inDefinedTermSet anzsrc-for:
119 rdf:type schema:DefinedTerm
120 sg:person.0762422112.05 schema:affiliation https://www.grid.ac/institutes/grid.16753.36
121 schema:familyName THOMPSON
122 schema:givenName CYNTHIA K
123 rdf:type schema:Person
124 https://www.grid.ac/institutes/grid.16753.36 schema:name NORTHWESTERN UNIVERSITY
125 rdf:type schema:Organization
126 https://www.grid.ac/institutes/grid.214431.1 schema:Organization
 




Preview window. Press ESC to close (or click here)


...