Impact of Feeding Interval of Preterms on the Time of Transition From Tube Feeding to Oral Feeding View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2016-2017

ABSTRACT

Preterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Investigators aimed to investigate the impact of 2-hourly feeding on time of transition from orogastric to oral feeding. Detailed Description Preterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Stomach volume of preterms varies a wide range of upto 20 ml. This should be taken into consideration during the process of feeding of preterms in neonatal intensive care unit. Trials were focused on early neonatal outcomes and it was found that duration of phototherapy and nasal noninvasive ventilation, and time to achieve full enteral feeds were shorter during 2-hourly feeding when compared to 3-hourly feeding, on the other hand 3-hourly feeding was shown to accelerate the stomach emptying. Besides, duration of catheterization, and ratio of feeding intolerance, apnea, and hypoglycemia were found to be similar infants who fed either 2 or 3-hourly. Investigators aimed to investigate the impact of two feeding regimens, 2-hourly or 3-hourly, on time of transition from orogastric to oral feeding in preterms. Patients and Methods: Preterms of birth weight less that 1500 gr and gestational age smaller than 32 weeks are going to be eligible for study if no congenital anomalies exist. Regarding current clinical protocol infants are fed every 2 hours until they weigh 1500 gr, and every 3 hours afterwards. At the day that the infants reach 1500 gr of body weight, a randomization will be performed in to two groups, Intervention group: Q2 interval (2-hourly feeding) or Control group: Q3 interval (3-hourly feeding), due to study protocol. Infants with inherited metabolic disorders, congenital anomalies, neonatal sepsis, and surgical diseases and the ones who fed with exclusively formula will be excluded. After randomization infants will be followed until discharge. The type of feeding, volume of each feed, weight gain per week, feeding intolerance (abdominal distention, vomiting, apnea, newly onset or increase of oxygen treatment demand), day of first oral feeding, time of transition from orogastric tube to oral feeding, duration of hospitalization will be recorded. More... »

URL

https://clinicaltrials.gov/show/NCT02916914

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3158", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "description": "Preterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Investigators aimed to investigate the impact of 2-hourly feeding on time of transition from orogastric to oral feeding.\n\nDetailed Description\nPreterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Stomach volume of preterms varies a wide range of upto 20 ml. This should be taken into consideration during the process of feeding of preterms in neonatal intensive care unit. Trials were focused on early neonatal outcomes and it was found that duration of phototherapy and nasal noninvasive ventilation, and time to achieve full enteral feeds were shorter during 2-hourly feeding when compared to 3-hourly feeding, on the other hand 3-hourly feeding was shown to accelerate the stomach emptying. Besides, duration of catheterization, and ratio of feeding intolerance, apnea, and hypoglycemia were found to be similar infants who fed either 2 or 3-hourly. Investigators aimed to investigate the impact of two feeding regimens, 2-hourly or 3-hourly, on time of transition from orogastric to oral feeding in preterms. Patients and Methods: Preterms of birth weight less that 1500 gr and gestational age smaller than 32 weeks are going to be eligible for study if no congenital anomalies exist. Regarding current clinical protocol infants are fed every 2 hours until they weigh 1500 gr, and every 3 hours afterwards. At the day that the infants reach 1500 gr of body weight, a randomization will be performed in to two groups, Intervention group: Q2 interval (2-hourly feeding) or Control group: Q3 interval (3-hourly feeding), due to study protocol. Infants with inherited metabolic disorders, congenital anomalies, neonatal sepsis, and surgical diseases and the ones who fed with exclusively formula will be excluded. After randomization infants will be followed until discharge. The type of feeding, volume of each feed, weight gain per week, feeding intolerance (abdominal distention, vomiting, apnea, newly onset or increase of oxygen treatment demand), day of first oral feeding, time of transition from orogastric tube to oral feeding, duration of hospitalization will be recorded.", 
    "endDate": "2017-08-01T00:00:00Z", 
    "id": "sg:clinicaltrial.NCT02916914", 
    "keywords": [
      "feeding", 
      "Time", 
      "transition", 
      "interval", 
      "neonatal intensive care unit", 
      "recommendation", 
      "World Health Organization", 
      "regimen", 
      "GR", 
      "infant", 
      "randomized controlled trial", 
      "stomach", 
      "wide range", 
      "upto", 
      "consideration", 
      "trial", 
      "neonatal outcome", 
      "duration", 
      "phototherapy", 
      "Noninvasive Ventilation", 
      "emptying", 
      "catheterization", 
      "ratio", 
      "intolerance", 
      "apnea", 
      "hypoglycemia", 
      "patient", 
      "birth weight", 
      "gestational age", 
      "congenital anomaly", 
      "Clinical Protocol", 
      "body weight", 
      "Random Allocation", 
      "intervention group", 
      "control group", 
      "study protocol", 
      "inherited metabolic disorder", 
      "neonatal sepsis", 
      "disease", 
      "formula", 
      "discharge", 
      "volume", 
      "feed", 
      "weight gain", 
      "distention", 
      "vomiting", 
      "onset", 
      "oxygen treatment", 
      "tube", 
      "hospitalization"
    ], 
    "name": "Impact of Feeding Interval of Preterms on the Time of Transition From Tube Feeding to Oral Feeding", 
    "sameAs": [
      "https://app.dimensions.ai/details/clinical_trial/NCT02916914"
    ], 
    "sdDataset": "clinical_trials", 
    "sdDatePublished": "2019-03-07T15:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "file:///pack/app/us_ct_data_00022.json", 
    "startDate": "2016-09-01T00:00:00Z", 
    "subjectOf": [
      {
        "id": "https://doi.org/10.1080/14767050802385749", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015796106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/apa.12291", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028516198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jp.2010.153", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040971189", 
          "https://doi.org/10.1038/jp.2010.153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1651-2227.2008.00774.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049677540"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "type": "MedicalStudy", 
    "url": "https://clinicaltrials.gov/show/NCT02916914"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/clinicaltrial.NCT02916914'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/clinicaltrial.NCT02916914'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/clinicaltrial.NCT02916914'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/clinicaltrial.NCT02916914'


 

This table displays all metadata directly associated to this object as RDF triples.

80 TRIPLES      15 PREDICATES      68 URIs      59 LITERALS      1 BLANK NODES

Subject Predicate Object
1 sg:clinicaltrial.NCT02916914 schema:about anzsrc-for:3158
2 schema:description Preterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Investigators aimed to investigate the impact of 2-hourly feeding on time of transition from orogastric to oral feeding. Detailed Description Preterms are usually fed with intervals of either two or three hours during their stay in neonatal intensive care unit. Recommendations of World Health Organization about feeding regimens, 3-hourly for infants 1500 - 2000 gr, and 2-hourly for infants 1000 - 1500 gr, are not proposed with regards to results of randomized controlled trials. Stomach volume of preterms varies a wide range of upto 20 ml. This should be taken into consideration during the process of feeding of preterms in neonatal intensive care unit. Trials were focused on early neonatal outcomes and it was found that duration of phototherapy and nasal noninvasive ventilation, and time to achieve full enteral feeds were shorter during 2-hourly feeding when compared to 3-hourly feeding, on the other hand 3-hourly feeding was shown to accelerate the stomach emptying. Besides, duration of catheterization, and ratio of feeding intolerance, apnea, and hypoglycemia were found to be similar infants who fed either 2 or 3-hourly. Investigators aimed to investigate the impact of two feeding regimens, 2-hourly or 3-hourly, on time of transition from orogastric to oral feeding in preterms. Patients and Methods: Preterms of birth weight less that 1500 gr and gestational age smaller than 32 weeks are going to be eligible for study if no congenital anomalies exist. Regarding current clinical protocol infants are fed every 2 hours until they weigh 1500 gr, and every 3 hours afterwards. At the day that the infants reach 1500 gr of body weight, a randomization will be performed in to two groups, Intervention group: Q2 interval (2-hourly feeding) or Control group: Q3 interval (3-hourly feeding), due to study protocol. Infants with inherited metabolic disorders, congenital anomalies, neonatal sepsis, and surgical diseases and the ones who fed with exclusively formula will be excluded. After randomization infants will be followed until discharge. The type of feeding, volume of each feed, weight gain per week, feeding intolerance (abdominal distention, vomiting, apnea, newly onset or increase of oxygen treatment demand), day of first oral feeding, time of transition from orogastric tube to oral feeding, duration of hospitalization will be recorded.
3 schema:endDate 2017-08-01T00:00:00Z
4 schema:keywords Clinical Protocol
5 GR
6 Noninvasive Ventilation
7 Random Allocation
8 Time
9 World Health Organization
10 apnea
11 birth weight
12 body weight
13 catheterization
14 congenital anomaly
15 consideration
16 control group
17 discharge
18 disease
19 distention
20 duration
21 emptying
22 feed
23 feeding
24 formula
25 gestational age
26 hospitalization
27 hypoglycemia
28 infant
29 inherited metabolic disorder
30 interval
31 intervention group
32 intolerance
33 neonatal intensive care unit
34 neonatal outcome
35 neonatal sepsis
36 onset
37 oxygen treatment
38 patient
39 phototherapy
40 randomized controlled trial
41 ratio
42 recommendation
43 regimen
44 stomach
45 study protocol
46 transition
47 trial
48 tube
49 upto
50 volume
51 vomiting
52 weight gain
53 wide range
54 schema:name Impact of Feeding Interval of Preterms on the Time of Transition From Tube Feeding to Oral Feeding
55 schema:sameAs https://app.dimensions.ai/details/clinical_trial/NCT02916914
56 schema:sdDatePublished 2019-03-07T15:26
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher N3e0c5948baaf42a59b77dffe0066cdf3
59 schema:startDate 2016-09-01T00:00:00Z
60 schema:subjectOf sg:pub.10.1038/jp.2010.153
61 https://doi.org/10.1080/14767050802385749
62 https://doi.org/10.1111/apa.12291
63 https://doi.org/10.1111/j.1651-2227.2008.00774.x
64 schema:url https://clinicaltrials.gov/show/NCT02916914
65 sgo:license sg:explorer/license/
66 sgo:sdDataset clinical_trials
67 rdf:type schema:MedicalStudy
68 N3e0c5948baaf42a59b77dffe0066cdf3 schema:name Springer Nature - SN SciGraph project
69 rdf:type schema:Organization
70 anzsrc-for:3158 schema:inDefinedTermSet anzsrc-for:
71 rdf:type schema:DefinedTerm
72 sg:pub.10.1038/jp.2010.153 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040971189
73 https://doi.org/10.1038/jp.2010.153
74 rdf:type schema:CreativeWork
75 https://doi.org/10.1080/14767050802385749 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015796106
76 rdf:type schema:CreativeWork
77 https://doi.org/10.1111/apa.12291 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028516198
78 rdf:type schema:CreativeWork
79 https://doi.org/10.1111/j.1651-2227.2008.00774.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049677540
80 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...