Urinary Circulating Tumor DNA Detection in Non-small Cell Lung Cancer: a Prospective Study View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2016-2020

ABSTRACT

This study will evaluate the feasibility and effectiveness of urinary ctDNA detection and dynamic monitoring during treatment of NSCLC patients prospectively,by collecting and detecting tumor tissues, peripheral blood samples and urine samples of NSCLC patients. Detailed Description Liquid biopsy, specifically through the assessment of circulating tumor DNA(ctDNA) from peripheral blood, has shown great promise in lung cancer diagnosis and therapeutic monitoring. Urinary samples are completely non-invasive and easily obtainable compared to blood and tissue extraction. To date, only a limited number of published studies have examined the feasibility of ctDNA detection from urine. This study will collect tumor tissues, pretreatment peripheral blood samples and urine samples from different TNM stages of NSCLC patients, and detect EGFR gene mutations in paired samples. More... »

URL

https://clinicaltrials.gov/show/NCT02907606

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