Validation of DNA Methylation Biomarkers for Oral Cancer Detection View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2015-2017

ABSTRACT

The purpose of this study is to investigate the correlation between DNA methylation and the treatment and recurrence of oral cancer. Detailed Description In this study, investigators plan to recruit 40~50 patients who had, or currently has oral cancer. The study procedures are as below: - After the Informed Consent Form is signed, swab from the lesion site and normal site to obtain oral epithelial cells. - Collect tissue from the tumor site and the non-cancerous matched site from the surgery or the tissue bank. - Collect oral swab from the lesion site and the normal site when patients return to the clinic for a regular follow-up. Specimens will be collected for DNA methylation testing, and the results will be compared with patient's clinical diagnosis. It is expected that the relationship between DNA methylation, oral cancer, and the recurrence of oral cancer will be found. More... »

URL

https://clinicaltrials.gov/show/NCT02648789

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