A Phase 1 Dose Escalation and Pharmacokinetic Study of Alisertib (MLN8237), an Aurora A Kinase Inhibitor, in Adult East Asian ... View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2012-2013

ABSTRACT

This is an open-label, multicenter, phase 1 study of alisertib in East Asian patients (eg, patients from countries including but not limited to Singapore, Hong Kong, Taiwan, and South Korea) with either relapsed or refractory advanced solid tumors or lymphomas for which no effective standard treatment is available.

URL

https://clinicaltrials.gov/show/NCT01512758

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3142", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "description": "This is an open-label, multicenter, phase 1 study of alisertib in East Asian patients (eg, patients from countries including but not limited to Singapore, Hong Kong, Taiwan, and South Korea) with either relapsed or refractory advanced solid tumors or lymphomas for which no effective standard treatment is available.", 
    "endDate": "2013-11-01T00:00:00Z", 
    "id": "sg:clinicaltrial.NCT01512758", 
    "keywords": [
      "patient", 
      "country", 
      "pharmacokinetic study", 
      "Phase 1 study", 
      "Taiwan", 
      "Hong Kong", 
      "advanced solid tumor", 
      "multicenter", 
      "lymphoma", 
      "East asian", 
      "Phase 1", 
      "standard treatment", 
      "Singapore", 
      "kinase inhibitor", 
      "Republic of Korea", 
      "dose escalation"
    ], 
    "name": "A Phase 1 Dose Escalation and Pharmacokinetic Study of Alisertib (MLN8237), an Aurora A Kinase Inhibitor, in Adult East Asian Patients With Advanced Solid Tumors or Lymphomas", 
    "sameAs": [
      "https://app.dimensions.ai/details/clinical_trial/NCT01512758"
    ], 
    "sdDataset": "clinical_trials", 
    "sdDatePublished": "2019-03-07T15:24", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "file:///pack/app/us_ct_data_00011.json", 
    "sponsor": [
      {
        "id": "https://www.grid.ac/institutes/grid.419849.9", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.410724.4", 
        "type": "Organization"
      }
    ], 
    "startDate": "2012-02-01T00:00:00Z", 
    "subjectOf": [
      {
        "id": "sg:pub.10.1007/s10637-015-0258-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019063283", 
          "https://doi.org/10.1007/s10637-015-0258-y"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "type": "MedicalStudy", 
    "url": "https://clinicaltrials.gov/show/NCT01512758"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/clinicaltrial.NCT01512758'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/clinicaltrial.NCT01512758'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/clinicaltrial.NCT01512758'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/clinicaltrial.NCT01512758'


 

This table displays all metadata directly associated to this object as RDF triples.

41 TRIPLES      16 PREDICATES      33 URIs      25 LITERALS      1 BLANK NODES

Subject Predicate Object
1 sg:clinicaltrial.NCT01512758 schema:about anzsrc-for:3142
2 schema:description This is an open-label, multicenter, phase 1 study of alisertib in East Asian patients (eg, patients from countries including but not limited to Singapore, Hong Kong, Taiwan, and South Korea) with either relapsed or refractory advanced solid tumors or lymphomas for which no effective standard treatment is available.
3 schema:endDate 2013-11-01T00:00:00Z
4 schema:keywords East asian
5 Hong Kong
6 Phase 1
7 Phase 1 study
8 Republic of Korea
9 Singapore
10 Taiwan
11 advanced solid tumor
12 country
13 dose escalation
14 kinase inhibitor
15 lymphoma
16 multicenter
17 patient
18 pharmacokinetic study
19 standard treatment
20 schema:name A Phase 1 Dose Escalation and Pharmacokinetic Study of Alisertib (MLN8237), an Aurora A Kinase Inhibitor, in Adult East Asian Patients With Advanced Solid Tumors or Lymphomas
21 schema:sameAs https://app.dimensions.ai/details/clinical_trial/NCT01512758
22 schema:sdDatePublished 2019-03-07T15:24
23 schema:sdLicense https://scigraph.springernature.com/explorer/license/
24 schema:sdPublisher Nf50432b7b6444e1f87ab83e80e1f8c58
25 schema:sponsor https://www.grid.ac/institutes/grid.410724.4
26 https://www.grid.ac/institutes/grid.419849.9
27 schema:startDate 2012-02-01T00:00:00Z
28 schema:subjectOf sg:pub.10.1007/s10637-015-0258-y
29 schema:url https://clinicaltrials.gov/show/NCT01512758
30 sgo:license sg:explorer/license/
31 sgo:sdDataset clinical_trials
32 rdf:type schema:MedicalStudy
33 Nf50432b7b6444e1f87ab83e80e1f8c58 schema:name Springer Nature - SN SciGraph project
34 rdf:type schema:Organization
35 anzsrc-for:3142 schema:inDefinedTermSet anzsrc-for:
36 rdf:type schema:DefinedTerm
37 sg:pub.10.1007/s10637-015-0258-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1019063283
38 https://doi.org/10.1007/s10637-015-0258-y
39 rdf:type schema:CreativeWork
40 https://www.grid.ac/institutes/grid.410724.4 schema:Organization
41 https://www.grid.ac/institutes/grid.419849.9 schema:Organization
 




Preview window. Press ESC to close (or click here)


...