The LIFE Study - Lifestyle Interventions and Independence for Elders View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2010-2014

ABSTRACT

Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized controlled trial is being conducted to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older adults who are followed for an average of 2.7 years. The primary aim was to assess the long-term effects of the proposed interventions on the primary outcome of major mobility disability, defined as inability to walk 400 m. Detailed Description As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamental feature of human functioning. Older people who lose mobility are less likely to remain in the community, have higher rates of morbidity, mortality, and hospitalizations and experience a poorer quality of life. Several studies have shown that regular physical activity improves physical performance, but definitive evidence showing that mobility disability can be prevented was lacking. A Phase 3 randomized controlled trial was needed to fill this evidence gap. The LIFE Study was a Phase 3, multicenter randomized controlled trial (RCT) designed to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older persons who are followed for an average of 2.7 years. The primary outcome was major mobility disability, defined as inability to walk 400 m. Secondary outcomes include cognitive function based on the Digit Symbol Substitution Test (DSST) and the Hopkins Verbal Learning Test (HVLT); serious fall injuries; persistent mobility disability; the combined outcome of major mobility disability or death; disability in activities of daily living; and cost-effectiveness. Tertiary outcomes include the combined outcome of mild cognitive impairment or dementia, a composite measure of the cognitive assessment battery, physical performance within pre-specified subgroups defined on the basis of race, gender and baseline physical performance, sleep-wake disturbances, dyspnea, ventilatory capacity, cardiopulmonary events, and cardiovascular events. The physical activity intervention consists primarily of walking at moderate intensity, lower extremity resistance exercises, balance exercises, stretching and behavioral counseling. The successful aging intervention consists of health education seminars regarding health-related matters and upper extremity stretching exercises. This trial provides definitive evidence regarding whether physical activity is effective and practical for preventing major mobility disability. These results will have crucial implications for public health prevention in a rapidly aging society, and will fill an important gap in knowledge for practicing evidence-based geriatric medicine. The study will also yield valuable information concerning the efficacy and effectiveness of physical activity across a broad spectrum of important health outcomes. The study will impact both clinical practice and public health policy, and will, therefore, benefit individuals and society. The Coordinating Center was at the University of Florida and the Data Management Analysis and Quality Control Center (DMAQC) was at Wake Forest University School of Medicine. The 8 field sites participating in the LIFE Study are University of Florida, Gainesville, Florida; Northwestern University, Chicago, Illinois; Pennington Biomedical Research Center, Baton Rouge, Louisiana; University of Pittsburgh, Pittsburgh, Pennsylvania; Stanford University, Palo Alto, California; Tufts University, Boston, Massachusetts; Wake Forest University, Winston-Salem, North Carolina; and Yale University, New Haven, Connecticut. More... »

URL

https://clinicaltrials.gov/show/NCT01072500

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3177", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3053", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "description": "Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized controlled trial is being conducted to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older adults who are followed for an average of 2.7 years. The primary aim was to assess the long-term effects of the proposed interventions on the primary outcome of major mobility disability, defined as inability to walk 400 m.\n\nDetailed Description\nAs life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamental feature of human functioning. Older people who lose mobility are less likely to remain in the community, have higher rates of morbidity, mortality, and hospitalizations and experience a poorer quality of life. Several studies have shown that regular physical activity improves physical performance, but definitive evidence showing that mobility disability can be prevented was lacking. A Phase 3 randomized controlled trial was needed to fill this evidence gap. The LIFE Study was a Phase 3, multicenter randomized controlled trial (RCT) designed to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older persons who are followed for an average of 2.7 years. The primary outcome was major mobility disability, defined as inability to walk 400 m. Secondary outcomes include cognitive function based on the Digit Symbol Substitution Test (DSST) and the Hopkins Verbal Learning Test (HVLT); serious fall injuries; persistent mobility disability; the combined outcome of major mobility disability or death; disability in activities of daily living; and cost-effectiveness. Tertiary outcomes include the combined outcome of mild cognitive impairment or dementia, a composite measure of the cognitive assessment battery, physical performance within pre-specified subgroups defined on the basis of race, gender and baseline physical performance, sleep-wake disturbances, dyspnea, ventilatory capacity, cardiopulmonary events, and cardiovascular events. The physical activity intervention consists primarily of walking at moderate intensity, lower extremity resistance exercises, balance exercises, stretching and behavioral counseling. The successful aging intervention consists of health education seminars regarding health-related matters and upper extremity stretching exercises. This trial provides definitive evidence regarding whether physical activity is effective and practical for preventing major mobility disability. These results will have crucial implications for public health prevention in a rapidly aging society, and will fill an important gap in knowledge for practicing evidence-based geriatric medicine. The study will also yield valuable information concerning the efficacy and effectiveness of physical activity across a broad spectrum of important health outcomes. The study will impact both clinical practice and public health policy, and will, therefore, benefit individuals and society. The Coordinating Center was at the University of Florida and the Data Management Analysis and Quality Control Center (DMAQC) was at Wake Forest University School of Medicine. The 8 field sites participating in the LIFE Study are University of Florida, Gainesville, Florida; Northwestern University, Chicago, Illinois; Pennington Biomedical Research Center, Baton Rouge, Louisiana; University of Pittsburgh, Pittsburgh, Pennsylvania; Stanford University, Palo Alto, California; Tufts University, Boston, Massachusetts; Wake Forest University, Winston-Salem, North Carolina; and Yale University, New Haven, Connecticut.", 
    "endDate": "2014-12-01T00:00:00Z", 
    "id": "sg:clinicaltrial.NCT01072500", 
    "keywords": [
      "life study", 
      "lifestyle intervention", 
      "elder", 
      "promising result", 
      "Pilot Project", 
      "old adult", 
      "physical activity intervention", 
      "health education intervention", 
      "multi-center", 
      "moderate intensity physical activity", 
      "health education program", 
      "average", 
      "primary aim", 
      "Time", 
      "intervention", 
      "primary outcome", 
      "mobility disability", 
      "inability", 
      "detailed description", 
      "life expectancy", 
      "United State", 
      "rise", 
      "independence", 
      "old american", 
      "public health priority", 
      "locomotion", 
      "assistance", 
      "fundamental feature", 
      "Older people", 
      "mobility", 
      "Residence Characteristic", 
      "high rate", 
      "morbidity", 
      "mortality", 
      "hospitalization", 
      "poor quality", 
      "life", 
      "regular physical activity", 
      "physical performance", 
      "definitive evidence", 
      "phase 3", 
      "evidence gap", 
      "multicenter", 
      "RCT", 
      "old person", 
      "Secondary outcome", 
      "cognitive function", 
      "substitution", 
      "Learning", 
      "Wound and Injury", 
      "combined outcome", 
      "death", 
      "disability", 
      "cost-effectiveness", 
      "mild cognitive impairment", 
      "dementia", 
      "composite measure", 
      "cognitive assessment", 
      "subgroup", 
      "Continental Population Group", 
      "Gender Identity", 
      "sleep-wake disturbance", 
      "dyspnea", 
      "capacity", 
      "cardiovascular event", 
      "moderate intensity", 
      "low extremity", 
      "balance", 
      "stretching", 
      "behavioral counseling", 
      "successful aging", 
      "health education", 
      "related matter", 
      "Upper Extremity", 
      "trial", 
      "Motor Activity", 
      "implication", 
      "public health", 
      "aging society", 
      "important gap", 
      "geriatric medicine", 
      "valuable information", 
      "efficacy", 
      "effectiveness", 
      "broad spectrum", 
      "important health outcome", 
      "clinical practice", 
      "public health policy", 
      "benefit individual", 
      "society", 
      "Coordinating Center", 
      "University of Florida", 
      "data management", 
      "Wake Forest University School of Medicine", 
      "field site", 
      "Gainesville", 
      "Florida", 
      "Northwestern University", 
      "Chicago", 
      "Illinois", 
      "Pennington", 
      "Biomedical Research Center", 
      "Baton Rouge", 
      "Louisiana", 
      "Pittsburgh", 
      "Pennsylvania", 
      "Stanford University", 
      "Palo Alto", 
      "California", 
      "Tufts University", 
      "Boston", 
      "Massachusetts", 
      "Wake Forest University", 
      "Winston-Salem", 
      "North Carolina", 
      "Yale University", 
      "Haven", 
      "Connecticut"
    ], 
    "name": "The LIFE Study - Lifestyle Interventions and Independence for Elders", 
    "sameAs": [
      "https://app.dimensions.ai/details/clinical_trial/NCT01072500"
    ], 
    "sdDataset": "clinical_trials", 
    "sdDatePublished": "2019-03-07T15:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "file:///pack/app/us_ct_data_00008.json", 
    "sponsor": [
      {
        "id": "https://www.grid.ac/institutes/grid.429997.8", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.168010.e", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.47100.32", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.412860.9", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.279885.9", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.16753.36", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.15276.37", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.21925.3d", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.419475.a", 
        "type": "Organization"
      }
    ], 
    "startDate": "2010-02-01T00:00:00Z", 
    "subjectOf": [
      {
        "id": "https://doi.org/10.1001/jama.2014.5616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000288594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gps.3949", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001017877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.113.000257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001496213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/glr123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001730052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.13509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001780318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jech-2016-207321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002540862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0116058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003374267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/glt068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004910333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.14380", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005295812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.12738", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007191440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.i245", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011088139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/glt064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014581637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2015.9617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015816565"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/61.11.1157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024925581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.12845", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025355580"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ypmed.2016.12.049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026931513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamda.2014.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029237983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/cia.s49737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044641347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.114.001288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045987769"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamda.2015.03.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046306401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12966-015-0322-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049495127", 
          "https://doi.org/10.1186/s12966-015-0322-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.14114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050251953"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.14013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052733040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/glw001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059623238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/m16-0529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079331366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12916-017-0824-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084251051", 
          "https://doi.org/10.1186/s12916-017-0824-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12916-017-0824-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084251051", 
          "https://doi.org/10.1186/s12916-017-0824-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/oby.21860", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086274592"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.117.007215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1093138168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.conctc.2017.12.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099917774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.15369", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103202133"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "type": "MedicalStudy", 
    "url": "https://clinicaltrials.gov/show/NCT01072500"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/clinicaltrial.NCT01072500'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/clinicaltrial.NCT01072500'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/clinicaltrial.NCT01072500'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/clinicaltrial.NCT01072500'


 

This table displays all metadata directly associated to this object as RDF triples.

248 TRIPLES      16 PREDICATES      172 URIs      127 LITERALS      1 BLANK NODES

Subject Predicate Object
1 sg:clinicaltrial.NCT01072500 schema:about anzsrc-for:3053
2 anzsrc-for:3177
3 schema:description Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized controlled trial is being conducted to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older adults who are followed for an average of 2.7 years. The primary aim was to assess the long-term effects of the proposed interventions on the primary outcome of major mobility disability, defined as inability to walk 400 m. Detailed Description As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamental feature of human functioning. Older people who lose mobility are less likely to remain in the community, have higher rates of morbidity, mortality, and hospitalizations and experience a poorer quality of life. Several studies have shown that regular physical activity improves physical performance, but definitive evidence showing that mobility disability can be prevented was lacking. A Phase 3 randomized controlled trial was needed to fill this evidence gap. The LIFE Study was a Phase 3, multicenter randomized controlled trial (RCT) designed to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older persons who are followed for an average of 2.7 years. The primary outcome was major mobility disability, defined as inability to walk 400 m. Secondary outcomes include cognitive function based on the Digit Symbol Substitution Test (DSST) and the Hopkins Verbal Learning Test (HVLT); serious fall injuries; persistent mobility disability; the combined outcome of major mobility disability or death; disability in activities of daily living; and cost-effectiveness. Tertiary outcomes include the combined outcome of mild cognitive impairment or dementia, a composite measure of the cognitive assessment battery, physical performance within pre-specified subgroups defined on the basis of race, gender and baseline physical performance, sleep-wake disturbances, dyspnea, ventilatory capacity, cardiopulmonary events, and cardiovascular events. The physical activity intervention consists primarily of walking at moderate intensity, lower extremity resistance exercises, balance exercises, stretching and behavioral counseling. The successful aging intervention consists of health education seminars regarding health-related matters and upper extremity stretching exercises. This trial provides definitive evidence regarding whether physical activity is effective and practical for preventing major mobility disability. These results will have crucial implications for public health prevention in a rapidly aging society, and will fill an important gap in knowledge for practicing evidence-based geriatric medicine. The study will also yield valuable information concerning the efficacy and effectiveness of physical activity across a broad spectrum of important health outcomes. The study will impact both clinical practice and public health policy, and will, therefore, benefit individuals and society. The Coordinating Center was at the University of Florida and the Data Management Analysis and Quality Control Center (DMAQC) was at Wake Forest University School of Medicine. The 8 field sites participating in the LIFE Study are University of Florida, Gainesville, Florida; Northwestern University, Chicago, Illinois; Pennington Biomedical Research Center, Baton Rouge, Louisiana; University of Pittsburgh, Pittsburgh, Pennsylvania; Stanford University, Palo Alto, California; Tufts University, Boston, Massachusetts; Wake Forest University, Winston-Salem, North Carolina; and Yale University, New Haven, Connecticut.
4 schema:endDate 2014-12-01T00:00:00Z
5 schema:keywords Baton Rouge
6 Biomedical Research Center
7 Boston
8 California
9 Chicago
10 Connecticut
11 Continental Population Group
12 Coordinating Center
13 Florida
14 Gainesville
15 Gender Identity
16 Haven
17 Illinois
18 Learning
19 Louisiana
20 Massachusetts
21 Motor Activity
22 North Carolina
23 Northwestern University
24 Older people
25 Palo Alto
26 Pennington
27 Pennsylvania
28 Pilot Project
29 Pittsburgh
30 RCT
31 Residence Characteristic
32 Secondary outcome
33 Stanford University
34 Time
35 Tufts University
36 United State
37 University of Florida
38 Upper Extremity
39 Wake Forest University
40 Wake Forest University School of Medicine
41 Winston-Salem
42 Wound and Injury
43 Yale University
44 aging society
45 assistance
46 average
47 balance
48 behavioral counseling
49 benefit individual
50 broad spectrum
51 capacity
52 cardiovascular event
53 clinical practice
54 cognitive assessment
55 cognitive function
56 combined outcome
57 composite measure
58 cost-effectiveness
59 data management
60 death
61 definitive evidence
62 dementia
63 detailed description
64 disability
65 dyspnea
66 effectiveness
67 efficacy
68 elder
69 evidence gap
70 field site
71 fundamental feature
72 geriatric medicine
73 health education
74 health education intervention
75 health education program
76 high rate
77 hospitalization
78 implication
79 important gap
80 important health outcome
81 inability
82 independence
83 intervention
84 life
85 life expectancy
86 life study
87 lifestyle intervention
88 locomotion
89 low extremity
90 mild cognitive impairment
91 mobility
92 mobility disability
93 moderate intensity
94 moderate intensity physical activity
95 morbidity
96 mortality
97 multi-center
98 multicenter
99 old adult
100 old american
101 old person
102 phase 3
103 physical activity intervention
104 physical performance
105 poor quality
106 primary aim
107 primary outcome
108 promising result
109 public health
110 public health policy
111 public health priority
112 regular physical activity
113 related matter
114 rise
115 sleep-wake disturbance
116 society
117 stretching
118 subgroup
119 substitution
120 successful aging
121 trial
122 valuable information
123 schema:name The LIFE Study - Lifestyle Interventions and Independence for Elders
124 schema:sameAs https://app.dimensions.ai/details/clinical_trial/NCT01072500
125 schema:sdDatePublished 2019-03-07T15:23
126 schema:sdLicense https://scigraph.springernature.com/explorer/license/
127 schema:sdPublisher N1335a9250dde4ec788b2880a39954c73
128 schema:sponsor https://www.grid.ac/institutes/grid.15276.37
129 https://www.grid.ac/institutes/grid.16753.36
130 https://www.grid.ac/institutes/grid.168010.e
131 https://www.grid.ac/institutes/grid.21925.3d
132 https://www.grid.ac/institutes/grid.279885.9
133 https://www.grid.ac/institutes/grid.412860.9
134 https://www.grid.ac/institutes/grid.419475.a
135 https://www.grid.ac/institutes/grid.429997.8
136 https://www.grid.ac/institutes/grid.47100.32
137 schema:startDate 2010-02-01T00:00:00Z
138 schema:subjectOf sg:pub.10.1186/s12916-017-0824-6
139 sg:pub.10.1186/s12966-015-0322-1
140 https://doi.org/10.1001/jama.2014.5616
141 https://doi.org/10.1001/jama.2015.9617
142 https://doi.org/10.1002/gps.3949
143 https://doi.org/10.1002/oby.21860
144 https://doi.org/10.1016/j.conctc.2017.12.004
145 https://doi.org/10.1016/j.jamda.2014.05.008
146 https://doi.org/10.1016/j.jamda.2015.03.010
147 https://doi.org/10.1016/j.ypmed.2016.12.049
148 https://doi.org/10.1093/gerona/61.11.1157
149 https://doi.org/10.1093/gerona/glr123
150 https://doi.org/10.1093/gerona/glt064
151 https://doi.org/10.1093/gerona/glt068
152 https://doi.org/10.1093/gerona/glw001
153 https://doi.org/10.1111/jgs.12738
154 https://doi.org/10.1111/jgs.12845
155 https://doi.org/10.1111/jgs.13509
156 https://doi.org/10.1111/jgs.14013
157 https://doi.org/10.1111/jgs.14114
158 https://doi.org/10.1111/jgs.14380
159 https://doi.org/10.1111/jgs.15369
160 https://doi.org/10.1136/bmj.i245
161 https://doi.org/10.1136/jech-2016-207321
162 https://doi.org/10.1161/jaha.113.000257
163 https://doi.org/10.1161/jaha.114.001288
164 https://doi.org/10.1161/jaha.117.007215
165 https://doi.org/10.1371/journal.pone.0116058
166 https://doi.org/10.2147/cia.s49737
167 https://doi.org/10.7326/m16-0529
168 schema:url https://clinicaltrials.gov/show/NCT01072500
169 sgo:license sg:explorer/license/
170 sgo:sdDataset clinical_trials
171 rdf:type schema:MedicalStudy
172 N1335a9250dde4ec788b2880a39954c73 schema:name Springer Nature - SN SciGraph project
173 rdf:type schema:Organization
174 anzsrc-for:3053 schema:inDefinedTermSet anzsrc-for:
175 rdf:type schema:DefinedTerm
176 anzsrc-for:3177 schema:inDefinedTermSet anzsrc-for:
177 rdf:type schema:DefinedTerm
178 sg:pub.10.1186/s12916-017-0824-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084251051
179 https://doi.org/10.1186/s12916-017-0824-6
180 rdf:type schema:CreativeWork
181 sg:pub.10.1186/s12966-015-0322-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049495127
182 https://doi.org/10.1186/s12966-015-0322-1
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1001/jama.2014.5616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000288594
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1001/jama.2015.9617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015816565
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1002/gps.3949 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001017877
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1002/oby.21860 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086274592
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/j.conctc.2017.12.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099917774
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/j.jamda.2014.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029237983
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.jamda.2015.03.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046306401
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.ypmed.2016.12.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026931513
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1093/gerona/61.11.1157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024925581
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1093/gerona/glr123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001730052
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1093/gerona/glt064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014581637
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1093/gerona/glt068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004910333
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1093/gerona/glw001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059623238
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1111/jgs.12738 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007191440
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1111/jgs.12845 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025355580
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1111/jgs.13509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001780318
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1111/jgs.14013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052733040
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1111/jgs.14114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050251953
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1111/jgs.14380 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005295812
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1111/jgs.15369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103202133
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1136/bmj.i245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011088139
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1136/jech-2016-207321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002540862
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1161/jaha.113.000257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001496213
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1161/jaha.114.001288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045987769
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1161/jaha.117.007215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1093138168
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1371/journal.pone.0116058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003374267
235 rdf:type schema:CreativeWork
236 https://doi.org/10.2147/cia.s49737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044641347
237 rdf:type schema:CreativeWork
238 https://doi.org/10.7326/m16-0529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079331366
239 rdf:type schema:CreativeWork
240 https://www.grid.ac/institutes/grid.15276.37 schema:Organization
241 https://www.grid.ac/institutes/grid.16753.36 schema:Organization
242 https://www.grid.ac/institutes/grid.168010.e schema:Organization
243 https://www.grid.ac/institutes/grid.21925.3d schema:Organization
244 https://www.grid.ac/institutes/grid.279885.9 schema:Organization
245 https://www.grid.ac/institutes/grid.412860.9 schema:Organization
246 https://www.grid.ac/institutes/grid.419475.a schema:Organization
247 https://www.grid.ac/institutes/grid.429997.8 schema:Organization
248 https://www.grid.ac/institutes/grid.47100.32 schema:Organization
 




Preview window. Press ESC to close (or click here)


...