A Two-Cohort, Open-Label, Single and Multiple Dose Pharmacokinetic Study of 90 mg and 180 mg Doses of AZD6140 in Healthy ... View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

2008-2008

ABSTRACT

This will be a single centre study conducted at the 3rd hospital affiliated to Peking University. Approximately 24 healthy Chinese volunteers, male and female, will be recruited to obtain at least 20 evaluable volunteers. The primary objective of this study is to characterize the pharmacokinetics of AZD6140 and its active metabolite AR-C124910XX after single and multiple (twice daily) doses of AZD6140 90 mg and 180 mg in healthy Chinese volunteers. The secondary objective of this study is to determine the safety and tolerability of single and multiple (twice daily) 90 mg and 180 mg doses of AZD6140 by physical examination, clinical laboratory tests, vital signs, and collection of adverse events in healthy Chinese volunteers. More... »

URL

https://clinicaltrials.gov/show/NCT00721448

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3177", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "description": "This will be a single centre study conducted at the 3rd hospital affiliated to Peking University. Approximately 24 healthy Chinese volunteers, male and female, will be recruited to obtain at least 20 evaluable volunteers. The primary objective of this study is to characterize the pharmacokinetics of AZD6140 and its active metabolite AR-C124910XX after single and multiple (twice daily) doses of AZD6140 90 mg and 180 mg in healthy Chinese volunteers. The secondary objective of this study is to determine the safety and tolerability of single and multiple (twice daily) 90 mg and 180 mg doses of AZD6140 by physical examination, clinical laboratory tests, vital signs, and collection of adverse events in healthy Chinese volunteers.", 
    "endDate": "2008-08-01T00:00:00Z", 
    "id": "sg:clinicaltrial.NCT00721448", 
    "keywords": [
      "cohort", 
      "label", 
      "pharmacokinetic study", 
      "dose", 
      "volunteer", 
      "China", 
      "single-center study", 
      "hospital", 
      "Peking University", 
      "primary objective", 
      "pharmacokinetics", 
      "active metabolite", 
      "secondary objective", 
      "safety", 
      "tolerability", 
      "physical examination", 
      "clinical laboratory test", 
      "vital sign", 
      "collection", 
      "adverse event"
    ], 
    "name": "A Two-Cohort, Open-Label, Single and Multiple Dose Pharmacokinetic Study of 90 mg and 180 mg Doses of AZD6140 in Healthy Chinese Volunteers Living in China", 
    "sameAs": [
      "https://app.dimensions.ai/details/clinical_trial/NCT00721448"
    ], 
    "sdDataset": "clinical_trials", 
    "sdDatePublished": "2019-03-07T15:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "file:///pack/app/us_ct_data_00005.json", 
    "sponsor": [
      {
        "id": "https://www.grid.ac/institutes/grid.418152.b", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.11135.37", 
        "type": "Organization"
      }
    ], 
    "startDate": "2008-06-01T00:00:00Z", 
    "subjectOf": [
      {
        "id": "sg:pub.10.2165/11595930-000000000-00000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006237594", 
          "https://doi.org/10.2165/11595930-000000000-00000"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "type": "MedicalStudy", 
    "url": "https://clinicaltrials.gov/show/NCT00721448"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/clinicaltrial.NCT00721448'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/clinicaltrial.NCT00721448'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/clinicaltrial.NCT00721448'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/clinicaltrial.NCT00721448'


 

This table displays all metadata directly associated to this object as RDF triples.

45 TRIPLES      16 PREDICATES      37 URIs      29 LITERALS      1 BLANK NODES

Subject Predicate Object
1 sg:clinicaltrial.NCT00721448 schema:about anzsrc-for:3177
2 schema:description This will be a single centre study conducted at the 3rd hospital affiliated to Peking University. Approximately 24 healthy Chinese volunteers, male and female, will be recruited to obtain at least 20 evaluable volunteers. The primary objective of this study is to characterize the pharmacokinetics of AZD6140 and its active metabolite AR-C124910XX after single and multiple (twice daily) doses of AZD6140 90 mg and 180 mg in healthy Chinese volunteers. The secondary objective of this study is to determine the safety and tolerability of single and multiple (twice daily) 90 mg and 180 mg doses of AZD6140 by physical examination, clinical laboratory tests, vital signs, and collection of adverse events in healthy Chinese volunteers.
3 schema:endDate 2008-08-01T00:00:00Z
4 schema:keywords China
5 Peking University
6 active metabolite
7 adverse event
8 clinical laboratory test
9 cohort
10 collection
11 dose
12 hospital
13 label
14 pharmacokinetic study
15 pharmacokinetics
16 physical examination
17 primary objective
18 safety
19 secondary objective
20 single-center study
21 tolerability
22 vital sign
23 volunteer
24 schema:name A Two-Cohort, Open-Label, Single and Multiple Dose Pharmacokinetic Study of 90 mg and 180 mg Doses of AZD6140 in Healthy Chinese Volunteers Living in China
25 schema:sameAs https://app.dimensions.ai/details/clinical_trial/NCT00721448
26 schema:sdDatePublished 2019-03-07T15:23
27 schema:sdLicense https://scigraph.springernature.com/explorer/license/
28 schema:sdPublisher N599b36faa23a43f3860622cbf91deb8e
29 schema:sponsor https://www.grid.ac/institutes/grid.11135.37
30 https://www.grid.ac/institutes/grid.418152.b
31 schema:startDate 2008-06-01T00:00:00Z
32 schema:subjectOf sg:pub.10.2165/11595930-000000000-00000
33 schema:url https://clinicaltrials.gov/show/NCT00721448
34 sgo:license sg:explorer/license/
35 sgo:sdDataset clinical_trials
36 rdf:type schema:MedicalStudy
37 N599b36faa23a43f3860622cbf91deb8e schema:name Springer Nature - SN SciGraph project
38 rdf:type schema:Organization
39 anzsrc-for:3177 schema:inDefinedTermSet anzsrc-for:
40 rdf:type schema:DefinedTerm
41 sg:pub.10.2165/11595930-000000000-00000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006237594
42 https://doi.org/10.2165/11595930-000000000-00000
43 rdf:type schema:CreativeWork
44 https://www.grid.ac/institutes/grid.11135.37 schema:Organization
45 https://www.grid.ac/institutes/grid.418152.b schema:Organization
 




Preview window. Press ESC to close (or click here)


...