Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin View Homepage


Ontology type: schema:MedicalStudy     


Clinical Trial Info

YEARS

1998-2007

ABSTRACT

The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women. Detailed Description The effect of menopause on body composition and cardiovascular risk in healthy caucasian women has been the subject of much study. In contrast, there are few data available on menopause in African-American women. Since menopause is associated with potentially preventable health risks in women, this proposal is aimed at characterizing the perimenopausal period in terms of body fat, energy balance, and insulin action in both caucasian and African-American women. The study will address 4 general hypotheses: - Menopause increases both total and visceral abdominal fat - Changes in body composition and body weight at menopause are mediated, at least in part by changes in 24-hour energy expenditure and/or food intake - Menopause results in decreased insulin sensitivity that may predispose certain women to develop diabetes later in life - African-American women may respond to the shifts in reproductive hormones at menopause differently than caucasian women. More... »

URL

https://clinicaltrials.gov/show/NCT00412269

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3053", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "description": "The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women.\n\nDetailed Description\nThe effect of menopause on body composition and cardiovascular risk in healthy caucasian women has been the subject of much study. In contrast, there are few data available on menopause in African-American women. Since menopause is associated with potentially preventable health risks in women, this proposal is aimed at characterizing the perimenopausal period in terms of body fat, energy balance, and insulin action in both caucasian and African-American women. The study will address 4 general hypotheses: - Menopause increases both total and visceral abdominal fat - Changes in body composition and body weight at menopause are mediated, at least in part by changes in 24-hour energy expenditure and/or food intake - Menopause results in decreased insulin sensitivity that may predispose certain women to develop diabetes later in life - African-American women may respond to the shifts in reproductive hormones at menopause differently than caucasian women.", 
    "endDate": "2007-03-01T00:00:00Z", 
    "id": "sg:clinicaltrial.NCT00412269", 
    "keywords": [
      "transition", 
      "menopause", 
      "energy balance", 
      "insulin", 
      "obesity", 
      "obese woman", 
      "body composition", 
      "cardiovascular risk", 
      "Caucasian woman", 
      "contrast", 
      "African American woman", 
      "health risk", 
      "woman", 
      "period", 
      "adipose tissue", 
      "insulin action", 
      "general hypothesise", 
      "abdominal fat", 
      "body weight", 
      "energy", 
      "Eating", 
      "decreased insulin sensitivity", 
      "predispose", 
      "diabetes", 
      "life", 
      "shift", 
      "reproductive hormone"
    ], 
    "name": "Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin", 
    "sameAs": [
      "https://app.dimensions.ai/details/clinical_trial/NCT00412269"
    ], 
    "sdDataset": "clinical_trials", 
    "sdDatePublished": "2019-03-07T15:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "file:///pack/app/us_ct_data_00003.json", 
    "sponsor": [
      {
        "id": "https://www.grid.ac/institutes/grid.250514.7", 
        "type": "Organization"
      }, 
      {
        "id": "https://www.grid.ac/institutes/grid.94365.3d", 
        "type": "Organization"
      }
    ], 
    "startDate": "1998-02-01T00:00:00Z", 
    "subjectOf": [
      {
        "id": "sg:pub.10.1038/ijo.2008.25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050102605", 
          "https://doi.org/10.1038/ijo.2008.25"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "type": "MedicalStudy", 
    "url": "https://clinicaltrials.gov/show/NCT00412269"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/clinicaltrial.NCT00412269'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/clinicaltrial.NCT00412269'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/clinicaltrial.NCT00412269'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/clinicaltrial.NCT00412269'


 

This table displays all metadata directly associated to this object as RDF triples.

52 TRIPLES      16 PREDICATES      44 URIs      36 LITERALS      1 BLANK NODES

Subject Predicate Object
1 sg:clinicaltrial.NCT00412269 schema:about anzsrc-for:3053
2 schema:description The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women. Detailed Description The effect of menopause on body composition and cardiovascular risk in healthy caucasian women has been the subject of much study. In contrast, there are few data available on menopause in African-American women. Since menopause is associated with potentially preventable health risks in women, this proposal is aimed at characterizing the perimenopausal period in terms of body fat, energy balance, and insulin action in both caucasian and African-American women. The study will address 4 general hypotheses: - Menopause increases both total and visceral abdominal fat - Changes in body composition and body weight at menopause are mediated, at least in part by changes in 24-hour energy expenditure and/or food intake - Menopause results in decreased insulin sensitivity that may predispose certain women to develop diabetes later in life - African-American women may respond to the shifts in reproductive hormones at menopause differently than caucasian women.
3 schema:endDate 2007-03-01T00:00:00Z
4 schema:keywords African American woman
5 Caucasian woman
6 Eating
7 abdominal fat
8 adipose tissue
9 body composition
10 body weight
11 cardiovascular risk
12 contrast
13 decreased insulin sensitivity
14 diabetes
15 energy
16 energy balance
17 general hypothesise
18 health risk
19 insulin
20 insulin action
21 life
22 menopause
23 obese woman
24 obesity
25 period
26 predispose
27 reproductive hormone
28 shift
29 transition
30 woman
31 schema:name Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin
32 schema:sameAs https://app.dimensions.ai/details/clinical_trial/NCT00412269
33 schema:sdDatePublished 2019-03-07T15:22
34 schema:sdLicense https://scigraph.springernature.com/explorer/license/
35 schema:sdPublisher N29291df90f934bca989a147db81830f3
36 schema:sponsor https://www.grid.ac/institutes/grid.250514.7
37 https://www.grid.ac/institutes/grid.94365.3d
38 schema:startDate 1998-02-01T00:00:00Z
39 schema:subjectOf sg:pub.10.1038/ijo.2008.25
40 schema:url https://clinicaltrials.gov/show/NCT00412269
41 sgo:license sg:explorer/license/
42 sgo:sdDataset clinical_trials
43 rdf:type schema:MedicalStudy
44 N29291df90f934bca989a147db81830f3 schema:name Springer Nature - SN SciGraph project
45 rdf:type schema:Organization
46 anzsrc-for:3053 schema:inDefinedTermSet anzsrc-for:
47 rdf:type schema:DefinedTerm
48 sg:pub.10.1038/ijo.2008.25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050102605
49 https://doi.org/10.1038/ijo.2008.25
50 rdf:type schema:CreativeWork
51 https://www.grid.ac/institutes/grid.250514.7 schema:Organization
52 https://www.grid.ac/institutes/grid.94365.3d schema:Organization
 




Preview window. Press ESC to close (or click here)


...